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验证数据展示

  • WB analysis using 13194-1-AP (same clone as 13194-1-PBS)

    WB analysis using 13194-1-AP (same clone as 13194-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 13194-1-AP (FXR1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13194-1-PBS in a different storage buffer formulation.

  • IP experiment of mouse skeletal muscle using 13194-1-AP (same clone as 13194-1-PBS)

    IP experiment of mouse skeletal muscle using 13194-1-AP (same clone as 13194-1-PBS)

    IP result of anti-FXR1 (IP:13194-1-AP, 3ug; Detection:13194-1-AP 1:800) with mouse skeletal muscle tissue lysate 8000ug. This data was developed using the same antibody clone with 13194-1-PBS in a different storage buffer formulation.

  • IHC staining of human heart using 13194-1-AP (same clone as 13194-1-PBS)

    IHC staining of human heart using 13194-1-AP (same clone as 13194-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human heart using 13194-1-AP (FXR1 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 13194-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with FXR1 antibody included
  • IF Staining of HeLa using 13194-1-AP (same clone as 13194-1-PBS)

    IF Staining of HeLa using 13194-1-AP (same clone as 13194-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed HeLa cells using FXR1 antibody (13194-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 13194-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

FXR1 Polyclonal antibody, PBS Only

FXR1 Polyclonal Antibody for WB, IHC, IF/ICC, IP, Indirect ELISA
Cat No. 13194-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, IF/ICC, IP, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy FXR1 Ready-To-Use IHC Kit. FXR1 primary antibody included.

产品信息

13194-1-PBS targets FXR1 in WB, IHC, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, IF/ICC, IP, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag3873

Product name: Recombinant human FXR1 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-353 aa of BC028983

Sequence: MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEISEGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKTVKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKRVNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEY

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 fragile X mental retardation, autosomal homolog 1
别名
计算分子量 621 aa, 70 kDa
观测分子量70-80 kDa
GenBank蛋白编号BC028983
基因名称 FXR1
Gene ID (NCBI) 8087
RRIDAB_2110702
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDP51114
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Tumour necrosis factor-alpha (TNF-alpha) is a key mediator of inflammation in host defence against infection and in autoimmune disease. Its production is controlled post-transcriptionally by multiple RNA-binding proteins that interact with the TNF-alpha AU-rich element and regulate its expression; Fragile X mental retardation-related protein 1 (FXR1) is one of these. FXR1 (fragile-X-mental retardation-related protein 1) are RNA-binding proteins that have been demonstrated to impact miRNA-mediated, post-transcriptional gene regulation, and required for embryonic and postnatal development of muscle tissue. It can regulate intracellular transport and local translation of certain mRNAs. The FXR1 exists some isoforms with the MW 69 kDa and 60 kDa.

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