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验证数据展示

  • WB analysis using 84449-1-RR (same clone as 84449-1-PBS)

    WB analysis using 84449-1-RR (same clone as 84449-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84449-1-RR (XPO4 antibody) at dilution of 1:8500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84449-1-PBS in a different storage buffer formulation.

  • IF Staining of K-562 using 84449-1-RR (same clone as 84449-1-PBS)

    IF Staining of K-562 using 84449-1-RR (same clone as 84449-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed K-562 cells using Exportin 4 antibody (84449-1-RR, Clone: 241443A5 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84449-1-PBS in a different storage buffer formulation.

  • FC experiment of HeLa using 84449-1-RR (same clone as 84449-1-PBS)

    FC experiment of HeLa using 84449-1-RR (same clone as 84449-1-PBS)

    1x10^6 HeLa cells were intracellularly stained with 0.25 ug Exportin 4 Recombinant antibody (84449-1-RR, Clone:241443A5) and APC-Conjugated Goat Anti-Rabbit IgG(H+L)(red), or 0.25 ug Isotype Control (blue). Cells were fixed and permeabilized with True-Nuclear Transcription Factor Buffer Set. This data was developed using the same antibody clone with 84449-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84449-1-RR

    Affinity and Kinetic Characterization of 84449-1-RR

    Biolayer interferometry (BLl) kinetic assays of 84449-1-RR against Human Exportin 4 were performed. The affinity constant is 0.512 nM.

Exportin 4 Recombinant antibody, PBS Only

Exportin 4 Uni-rAbTM Recombinant Antibody for WB, IF/ICC, FC (Intra), Indirect ELISA
Cat No. 84449-1-PBS

产品说明书

CloneNo. 241443A5

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IF/ICC, FC (Intra), Indirect ELISA

别名

XPO4, 241443A5, Exp4, Exportin-4, KIAA1721

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

84449-1-PBS targets Exportin 4 in WB, IF/ICC, FC (Intra), Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IF/ICC, FC (Intra), Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 Exportin 4 fusion protein Ag21845 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 exportin 4
别名 XPO4, 241443A5, Exp4, Exportin-4, KIAA1721
计算分子量 1151 aa, 130 kDa
观测分子量130 kDa
GenBank蛋白编号BC113571
基因名称 Exportin 4/XPO4
Gene ID (NCBI) 64328
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDQ9C0E2
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

exportin 4 (XPO4) maps to chromosome 13q and belongs to the importin β family which acts as a bidirectional nuclear transport receptor. Decreased XPO4 expression has been shown to associate with hepatocellular carcinoma. A genome-wide copy number variation (CNV) association study in a small cohort of Malaysian subjects identified a CNV in XPO4 to be correlated with the progression of metabolic (dysfunction) associated fatty liver disease (MAFLD). (PMID: 34388518)