Mouse Endoglin/CD105 Recombinant antibody, PBS Only

Endoglin/CD105 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 84807-5-PBS

产品说明书

CloneNo. 242305A11

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

WB, Indirect ELISA

CD105, 242305A11, S endoglin, Eng, endoglin

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -


产品信息

84807-5-PBS targets Endoglin/CD105 in WB, Indirect ELISA applications and shows reactivity with mouse samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 mouse
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 endoglin
别名 CD105, 242305A11, S endoglin, Eng, endoglin
计算分子量70kDa
观测分子量90 kDa
GenBank蛋白编号NM_007932.2
基因名称 CD105
Gene ID (NCBI) 13805
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDQ63961
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disulphide-linked subunits of 90-95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascular endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascular development and remodelling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis. (PMID: 1326540; 14528280; 21737653; 12773481)

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