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验证数据展示

  • WB analysis of HUVEC using 66537-1-Ig (same clone as 66537-1-PBS)

    WB analysis of HUVEC using 66537-1-Ig (same clone as 66537-1-PBS)

    HUVEC, HEK-293 and U-251 cells were subjected to SDS PAGE followed by western blot with 66537-1-Ig (EXOC3L2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66537-1-PBS in a different storage buffer formulation.

  • IF Staining of HUVEC using 66537-1-Ig (same clone as 66537-1-PBS)

    IF Staining of HUVEC using 66537-1-Ig (same clone as 66537-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed HUVEC cells using EXOC3L2 antibody (66537-1-Ig, Clone: 3C1C2 ) at dilution of 1:800 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66537-1-PBS in a different storage buffer formulation.

EXOC3L2 Monoclonal antibody, PBS Only

EXOC3L2 Monoclonal Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 66537-1-PBS

产品说明书

CloneNo. 3C1C2

宿主/亚型

Mouse / IgG1

种属反应性

Human

应用

WB, IF/ICC, Indirect ELISA

别名

EXOC3L2, XTP7

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

66537-1-PBS targets EXOC3L2 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with Human samples.

经测试应用 WB, IF/ICC, Indirect ELISA Application Description
经测试反应性 Human
免疫原 EXOC3L2 fusion protein Ag26912 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 exocyst complex component 3-like 2
别名 EXOC3L2, XTP7
计算分子量 46 kDa
观测分子量 46 kDa
GenBank蛋白编号BC104947
基因名称 EXOC3L2
Gene ID (NCBI) 90332
RRIDAB_2881900
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDQ2M3D2
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The exocyst is a protein complex that ensures spatial targeting of exocytotic vesicles to the plasma membrane. Exocyst complex component 3-like 2 (EXOC3L2) associates with the exocyst complex and mediates directional migration of endothelial cells (PMID: 21566143). The gene of human EXOC3L2 maps to chromosome 19q13.32 and encodes a deduced 409-amino acid protein with a calculated molecular mass of about 46 kDa. Mouse Exoc3l2 gene encodes an approximately 250-amino acid protein that lacks the N-terminal domain of human EXOC3L2. Mutations in EXOC3L2 gene may be associated with Alzheimer's disease.