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验证数据展示

  • FC experiment of human peripheral blood leukocytes using 98412-2-RR

    FC experiment of human peripheral blood leukocytes using 98412-2-RR

    1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human DcR2 Rabbit RecAb (98412-2-RR, Clone: 242916D5) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

  • FC experiment of human peripheral blood leukocytes using 98412-2-RR

    FC experiment of human peripheral blood leukocytes using 98412-2-RR

    1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human DcR2 Rabbit RecAb (98412-2-RR, Clone: 242916D5) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

Anti-Human DcR2 Rabbit Recombinant Antibody

DcR2 Recombinant Antibody for FC
Cat No. 98412-2-RR

产品说明书

CloneNo. 242916D5

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

CD264, Decoy receptor 2, TNF-related apoptosis-inducing ligand receptor 4, TNFRSF10D, TRAIL R4

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格价格库存

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经过测试的应用

Positive FC detected inhuman peripheral blood leukocytes

推荐稀释比

应用推荐稀释比
Flow Cytometry (FC)FC : 0.25 ug per 10^6 cells in a 100 µl suspension
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

98412-2-RR targets DcR2 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 DcR2 fusion protein Eg3487 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
别名 CD264, Decoy receptor 2, TNF-related apoptosis-inducing ligand receptor 4, TNFRSF10D, TRAIL R4
计算分子量42 kDa
GenBank蛋白编号NM_003840.5
基因名称 DcR2
Gene ID (NCBI) 8793
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDQ9UBN6
储存缓冲液 PBS with 0.09% sodium azide, pH 7.3.
储存条件Store at 2 - 8°C. Stable for one year after shipment.

背景介绍

Decoy receptor 2 (DcR2) is a member of the tumor necrosis factor receptor (TNFR) superfamily. It functions as a decoy receptor for TNF-related apoptosis-inducing ligand (TRAIL), thereby inhibiting TRAIL-mediated apoptosis (PMID: 15538968; 9537512). It has been considered a tentative marker of cellular senescence (PMID: 16079833; 22751116). Additionally, DCR2 has been implicated in the regulation of renal fibrosis and cell senescence, contributing to the pathogenesis of diabetic nephropathy (PMID: 35661704).

实验方案

Product Specific Protocols
FC protocol for DcR2 antibody 98412-2-RRDownload protocol
Standard Protocols
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