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验证数据展示

  • FC experiment of Transfected HEK-293T using 98205-1-RR (same clone as 98205-1-PBS)

    FC experiment of Transfected HEK-293T using 98205-1-RR (same clone as 98205-1-PBS)

    1x10^6 HEK-293T cells or DC-SIGNR/CD299 transfected HEK-293T cells were surface stained with 0.25 ug Anti-Human DC-SIGNR/CD299 Rabbit Recombinant Antibody (98205-1-RR, Clone: 241683G8) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98205-1-PBS in a different storage buffer formulation.

  • FC experiment of Transfected HEK-293T using 98205-1-RR (same clone as 98205-1-PBS)

    FC experiment of Transfected HEK-293T using 98205-1-RR (same clone as 98205-1-PBS)

    1x10^6 HEK-293T cells or DC-SIGNR/CD299 transfected HEK-293T cells were surface stained with 0.25 ug Anti-Human DC-SIGNR/CD299 Rabbit Recombinant Antibody (98205-1-RR, Clone:241683G8) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98205-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98205-1-RR

    Affinity and Kinetic Characterization of 98205-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98205-1-RR against Human DC-SIGNR/CD299 were performed. The affinity constant is 3.68 nM.

Anti-Human DC-SIGNR/CD299 Rabbit Recombinant Antibody, PBS Only

DC-SIGNR/CD299 Uni-rAb® Recombinant Antibody for FC
Cat No. 98205-1-PBS

产品说明书

CloneNo. 241683G8

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

CLEC4M, CD299, CD209L1, CD209L, CD209 antigen-like protein 1

缓冲液配方:  PBS Only
PBS, Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy DC-SIGNR/CD299 Ready-To-Use IHC Kit. DC-SIGNR/CD299 primary antibody included.

产品信息

98205-1-PBS targets DC-SIGNR/CD299 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原

Recombinant Protein

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 C-type lectin domain family 4, member M
别名 CLEC4M, CD299, CD209L1, CD209L, CD209 antigen-like protein 1
计算分子量 45 kDa
GenBank蛋白编号BC038851
基因名称 DC-SIGNR/CD299
Gene ID (NCBI) 10332
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purfication
UNIPROT IDQ9H2X3
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Dendritic cell-specific intracellular adhesion molecule-3-grabbing non-integrin (DC-SIGN/CD209) and DC-SIGN related (DC-SIGNR/CD299/L-SIGN/CD209L/CLEC4M) are trans-membrane C-type lectins that are calcium-dependent carbohydrate-binding proteins, which can act as cell-adhesion and pathogen-recognition receptors (PMID: 18458800). DC-SIGN and DC-SIGNR share 77% amino acid identity (PMID: 10975799; 11226297). DC-SIGN is expressed on subsets of dendritic cells and macrophages while DC-SIGNR is restricted to endothelial cells of the liver, lymph nodes and placenta (PMID: 17509452). DC-SIGNR servers as a receptor for ICAM-3. It recognizes a wide range of evolutionarily divergent pathogens.

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