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验证数据展示

  • WB analysis using 88004-1-RR (same clone as 88004-1-PBS)

    WB analysis using 88004-1-RR (same clone as 88004-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 88004-1-RR (CXorf21 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 88004-1-PBS in a different storage buffer formulation.

  • WB analysis using 88004-1-RR (same clone as 88004-1-PBS)

    WB analysis using 88004-1-RR (same clone as 88004-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 88004-1-RR (CXorf21 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 88004-1-PBS in a different storage buffer formulation.

  • IF Staining of THP-1 using 88004-1-RR (same clone as 88004-1-PBS)

    IF Staining of THP-1 using 88004-1-RR (same clone as 88004-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed THP-1 cells using CXorf21 antibody (88004-1-RR, Clone: 260203H7 ) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 88004-1-PBS in a different storage buffer formulation.

CXorf21 Recombinant monoclonal antibody, PBS Only

CXorf21 Uni-rAb® Recombinant Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 88004-1-PBS

产品说明书

CloneNo. 260203H7

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IF/ICC, Indirect ELISA

别名

TASL, TLR adapter interacting with SLC15A4 on the lysosome

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy TASL/CXorf21 Ready-To-Use IHC Kit. TASL/CXorf21 primary antibody included.

产品信息

88004-1-PBS targets CXorf21 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag32773

Product name: Recombinant human CXorf21 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-301 aa of BC020611

Sequence: MLSEGYLSGLEYWNDIHWSCASYNEQVAGEKEEETNSVATLSYSSVDETQVRSLYVSCKSSGKFISSVHSRESQHSRSQRVTVLQTNPNPVFESPNLAAVEICRDASRETYLVPSSCKSICKNYNDLQIAGGQVMAINSVTTDFPSESSFEYGPLLKSSEIPLPMEDSISTQPSDFPQKPIQRYSSYWRITSIKEKSSLQMQNPISNAVLNEYLEQKVVELYKQYIMDTVFHDSSPTQILASELIMTSVDQISLQVSREKNLETSKARDIVFSRLLQLMSTEITEISTPSLHISQYSNVNP

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 chromosome X open reading frame 21
别名 TASL, TLR adapter interacting with SLC15A4 on the lysosome
观测分子量34 kDa
GenBank蛋白编号BC020611
基因名称 CXorf21
Gene ID (NCBI) 80231
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDQ9HAI6
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CXorf21 (Chromosome X open reading frame 21) is also named as TASL and TLR adapter interacting with SLC15A4 on the lysosome. CXorf21 is an innate immune adapter that mediates the recruitment and activation of IRF5 downstream of endolysosomal toll-like receptors TLR7, TLR8 and TLR9 (PMID:32433612). CXorf21 plays a role in the regulation of endolysosomal pH in immune cells such as B-cells, dendritic cells and monocytes (PMID: 31001245). CXorf21 is a mediator of the X-chromosome gene dose-dependent increased risk of SLE in females (PMID: 31695690).

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