验证数据展示
产品信息
98078-1-PBS targets CTLA-4/CD152 in IHC, FC applications and shows reactivity with human samples.
| 经测试应用 | IHC, FC Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Eg0972 Product name: Recombinant Human CTLA4 protein (His Tag) Source: mammalian cells-derived, pHZ-KIsec-C-6*HIS Tag: C-6*HIS Domain: 36-161 aa of BC070162 Sequence: KAMHVAQPAVVLASSRGIASFVCEYASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTFLDDSICTGTSSGNQVNLTIQGLRAMDTGLYICKVELMYPPPYYLGIGNGTQIYVIDPEPCPDSD 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | cytotoxic T-lymphocyte-associated protein 4 |
| 别名 | CTLA4, 240793E8, CD152, CELIAC3, CTLA 4 |
| 计算分子量 | 223 aa, 25 kDa |
| GenBank蛋白编号 | BC070162 |
| 基因名称 | CTLA4 |
| Gene ID (NCBI) | 1493 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purfication |
| UNIPROT ID | P16410 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CTLA-4, also known as CD152, belonging to the immunoglobulin superfamily, is primarily found on activated T cells and regulatory T cells (Tregs). CTLA-4 is closely related to the T-cell costimulatory CD28, and both molecules bind to B7-1 and B7-2 on antigen-presenting cells. CTLA-4 acts as a negative regulatory molecule of T-cell responses.
