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验证数据展示

  • FC experiment of human PBMCs using 98078-1-RR (same clone as 98078-1-PBS)

    FC experiment of human PBMCs using 98078-1-RR (same clone as 98078-1-PBS)

    1x10^6 unstimulated or PHA stimulated human PBMCs were surface stained with 0.25 ug Anti-Human CTLA-4/CD152 Rabbit RecAb (98078-1-RR, Clone: 240793E8) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 647 Anti-Human CD3. Cells were not fixed. This data was developed using the same antibody clone with 98078-1-PBS in a different storage buffer formulation.

  • FC experiment of human PBMCs using 98078-1-RR (same clone as 98078-1-PBS)

    FC experiment of human PBMCs using 98078-1-RR (same clone as 98078-1-PBS)

    1x10^6 PHA-stimulated human PBMCs were surface stained with 0.25 ug Anti-Human CTLA-4/CD152 Rabbit RecAb (98078-1-RR, Clone: 240793E8)(red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue). 1x10^6 unstimulated human PBMCs were surface stained with Anti-Human CTLA-4/CD152 Rabbit Recombinant Antibody (98078-1-RR, Clone: 240793E8) (black, dashed) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98078-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98078-1-RR

    Affinity and Kinetic Characterization of 98078-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98078-1-RR against Human CTLA4/CD152 were performed. The affinity constant is 60.2 pM.

Anti-Human CTLA-4/CD152 Rabbit Recombinant Antibody, PBS Only

CTLA-4/CD152 Recombinant Antibody for FC
Cat No. 98078-1-PBS

产品说明书

CloneNo. 240793E8

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

CTLA4, 240793E8, CD152, CELIAC3, CTLA 4

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

98078-1-PBS targets CTLA-4/CD152 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 CTLA-4/CD152 fusion protein Eg0972 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 cytotoxic T-lymphocyte-associated protein 4
别名 CTLA4, 240793E8, CD152, CELIAC3, CTLA 4
计算分子量 223 aa, 25 kDa
GenBank蛋白编号BC070162
基因名称 CTLA4
Gene ID (NCBI) 1493
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purfication
UNIPROT IDP16410
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CTLA-4, also known as CD152, belonging to the immunoglobulin superfamily, is primarily found on activated T cells and regulatory T cells (Tregs). CTLA-4 is closely related to the T-cell costimulatory CD28, and both molecules bind to B7-1 and B7-2 on antigen-presenting cells. CTLA-4 acts as a negative regulatory molecule of T-cell responses.