验证数据展示
产品信息
33679-1-PBS targets CRYL1 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 |
CatNo: Ag38269 Product name: Recombinant human CRYL1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-319 aa of NM_015974.2 Sequence: MASSAAGCVVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAGSLKGSLSVEEQLSLISGCPNIQEAVEGAMHIQECVPEDLELKKKIFAQLDSIIDDRVILSSSTSCLMPSKLFAGLVHVKQCIVAHPVNPPYYIPLVELVPHPETAPTTVDRTHALMKKIGQCPMRVQKEVAGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSEGLGMRYAFIGPLETMHLNAEGMLSYCDRYSEGIKHVLQTFGPIPEFSRATAEKVNQDMCMKVPDDPEHLAARRQWRDECLMRLAKLKSQVQPQ 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | crystallin, lambda 1 |
| 别名 | CRY, EC:1.1.1.45, Gul3DH, Lambda-crystallin homolog, L-gulonate 3-dehydrogenase |
| 计算分子量 | 35kDa，319aa |
| 观测分子量 | 35 kDa |
| GenBank蛋白编号 | NM_015974.2 |
| 基因名称 | CRYL1 |
| Gene ID (NCBI) | 51084 |
| RRID | AB_3743046 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | Q9Y2S2 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CRYL1 (Crystallin Lambda 1) is a ubiquitously-expressed, dual-function protein that was first isolated from rabbit lens tissue. Human CRYL1 is encoded at chromosomal locus 13q12.11, contains two HCDH (3-hydroxyacyl-CoA dehydrogenase) domains, and is most abundant in liver and kidney, with only trace expression in peripheral-blood leukocytes and thymus. Further research showed that CRYL1 was expressed at lower levels in HCC tumors than in adjacent tissues, and this reduced expression was associated with advanced tumor staging, larger tumors, and decreased patient disease-free survival.
