• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0
Use Able AI chat for product recommendations

验证数据展示

  • WB analysis using 84924-7-RR (same clone as 84924-7-PBS)

    WB analysis using 84924-7-RR (same clone as 84924-7-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84924-7-RR (CNDP2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84924-7-PBS in a different storage buffer formulation.

  • IHC staining of rat stomach using 84924-7-RR (same clone as 84924-7-PBS)

    IHC staining of rat stomach using 84924-7-RR (same clone as 84924-7-PBS)

    Immunohistochemical analysis of paraffin-embedded rat stomach tissue slide using 84924-7-RR (CNDP2 antibody) at dilution of 1:2000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84924-7-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CNDP2 antibody included
  • IHC staining of rat stomach using 84924-7-RR (same clone as 84924-7-PBS)

    IHC staining of rat stomach using 84924-7-RR (same clone as 84924-7-PBS)

    Immunohistochemical analysis of paraffin-embedded rat stomach tissue slide using 84924-7-RR (CNDP2 antibody) at dilution of 1:2000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84924-7-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CNDP2 antibody included
  • Affinity and Kinetic Characterization of 84924-7-RR

    Affinity and Kinetic Characterization of 84924-7-RR

    Biolayer interferometry (BLl) kinetic assays of 84924-7-RR against Human CNDP2 were performed. The affinity constant is below 1 pM.

CNDP2 Recombinant monoclonal antibody, PBS Only

CNDP2 Uni-rAb® Recombinant Antibody for WB, IHC, Indirect ELISA
Cat No. 84924-7-PBS

产品说明书

CloneNo. 242373E4

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

242373E4, CNDP dipeptidase 2, CPGL, Cytosolic non-specific dipeptidase, EC:3.4.13.18

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

Planning an IHC experiment? We recommend our IHCeasy CNDP2 Ready-To-Use IHC Kit. CNDP2 primary antibody included.

产品信息

84924-7-PBS targets CNDP2 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag6684

Product name: Recombinant human CNDP2 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 124-475 aa of BC001375

Sequence: KLYGRGSTDDKGPVAGWINALEAYQKTGQEIPVNVRFCLEGMEESGSEGLDELIFARKDTFFKDVDYVCISDNYWLGKKKPCITYGLRGICYFFIEVECSNKDLHSGVYGGSVHEAMTDLILLMGSLVDKRGNILIPGINEAVAAVTEEEHKLYDDIDFDIEEFAKDVGAQILLHSHKKDILMHRWRYPSLSLHGIEGAFSGSGAKTVIPRKVVGKFSIRLVPNMTPEVVGEQVTSYLTKKFAELRSPNEFKVYMGHGGKPWVSDFSHPHYLAGRRAMKTVFGVEPDLTREGGSIPVTLTFQEATGKNVMLLPVGSADDGAHSQNEKLNRYNYIEGTKMLAAYLYEVSQLKD

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 CNDP dipeptidase 2 (metallopeptidase M20 family)
别名 242373E4, CNDP dipeptidase 2, CPGL, Cytosolic non-specific dipeptidase, EC:3.4.13.18
计算分子量 53 kDa
观测分子量 44-53 kDa
GenBank蛋白编号BC001375
基因名称 CNDP2
Gene ID (NCBI) 55748
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDQ96KP4
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Carnosine dipeptidase II (CNDP2) catalyzes the peptide bond hydrolysis in dipeptides, displaying a non-redundant activity toward threonyl dipeptides. It has high dipeptidase activity toward cysteinyl glycine, an intermediate metabolite in glutathione metabolism (PubMed:19346245, PubMed:12473676). Metabolizes N-lactoyl-amino acids, both through hydrolysis to form lactic acid and amino acids, as well as through their formation by reverse proteolysis (PubMed:25964343). CNDP2 has 2 isoforms with a molecular weight of 53 and 44 kDa.
The isoform 1 is ubiquitously expressed with higher levels in the kidney and liver (at protein level) and expressed in peripheral blood leukocytes (PubMed:12473676). It is also expressed in gastric mucosa and down-regulated in gastric cancer mucosal tissues (at the protein level) (PubMed:24395568). Isoform 2 is broadly expressed in fetal tissues and expressed in the adult liver and placenta. (PMID: 17121880).

||
New chat Able
正在加载，请稍候...