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验证数据展示

  • WB analysis of HeLa using 21013-1-AP (same clone as 21013-1-PBS)

    WB analysis of HeLa using 21013-1-AP (same clone as 21013-1-PBS)

    HeLa cells were subjected to SDS PAGE followed by western blot with 21013-1-AP (CLEC18A antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21013-1-PBS in a different storage buffer formulation.

  • IHC staining of human kidney using 21013-1-AP (same clone as 21013-1-PBS)

    IHC staining of human kidney using 21013-1-AP (same clone as 21013-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney using 21013-1-AP (CLEC18A antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 21013-1-PBS in a different storage buffer formulation.

  • IHC staining of human kidney using 21013-1-AP (same clone as 21013-1-PBS)

    IHC staining of human kidney using 21013-1-AP (same clone as 21013-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney using 21013-1-AP (CLEC18A antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 21013-1-PBS in a different storage buffer formulation.

CLEC18A Polyclonal antibody, PBS Only

CLEC18A Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 21013-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

MRLP2, MRCL1, MRCL, Mannose receptor-like protein 2, C-type lectin domain family 18 member A

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

21013-1-PBS targets CLEC18A in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag15237

Product name: Recombinant human CLEC18A protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 97-446 aa of BC141808

Sequence: ASGLWRTLQVGWNMQLLPAGLASFVEVVSLWFAEGQRYSHAAGECARNATCTHYMQLVWATSSQLGCGRHLCSAGQAAIEAFVCAYSPRGNWEVNGKTIVPYKKGAWCSLCTASVSGCFKAWDHAGGLCEVPRNPCRMSCQNHGRLNISTCHCHCPPGYTGRYCQVRCSLQCVHGRFREEECSCVCDIGYGGAQCATKVHFPFHTCDLRIDGDCFMVSSEADTYYRARMKCQRKGGVLAQIKRQKVQDILAFYLGRLETTNEVIDSDFETRNFWIGLTYKTAKDSFRWATGEHQAFTSFAFGQPDNHGFGNCVELQASAAFNWNDQRCKTRNRYICQFAQEHISRWGPGS

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 C-type lectin domain family 18, member A
别名 MRLP2, MRCL1, MRCL, Mannose receptor-like protein 2, C-type lectin domain family 18 member A
计算分子量 446 aa, 50 kDa
观测分子量 47-50 kDa
GenBank蛋白编号BC141808
基因名称 CLEC18A
Gene ID (NCBI) 348174
RRIDAB_10732842
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDA5D8T8
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CLEC18A, or C-type lectin member 18A, is a protein that plays a significant role in the human immune system, particularly in the context of viral infections. CLEC18A is widely expressed, with the highest levels found in myeloid cells and the liver. It is a co-receptor for TLR3 (Toll-like receptor 3) and is involved in enhancing the host's immune response to viral infections, such as H5N1 influenza A virus (IAV). CLEC18A has been implicated in the development of mixed cryoglobulinemia (MC), an extrahepatic manifestation associated with hepatitis C virus (HCV). This antibody can recognize CLEC18A/B/C.

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