验证数据展示
产品信息
98192-1-PBS targets CD16b in FC applications and shows reactivity with human samples.
经测试应用 | FC Application Description |
经测试反应性 | human |
免疫原 | Fusion Protein 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) |
别名 | FCGR3B, FCG3, Fc gamma RIIIb, Fc gamma RIII beta, Fc gamma RIII |
基因名称 | FCGR3B |
Gene ID (NCBI) | 2215 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purfication |
储存缓冲液 | PBS only, pH 7.3. |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CD16 is a low affinity Fc receptor. It has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b), encoded by two nearly identical genes, FCGR3A and FCGR3B. In humans, FcγRIIIa/CD16a is a type I transmembrane receptor expressed on macrophages and NK cells. FcγRIIIb/CD16b is a GPI-linked Fc-receptor highly expressed on neutrophils. The two proteins differ by only four amino acid residues in the mature proteins (PMID: 30361439).