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验证数据展示

  • FC experiment of human peripheral blood leukocytes using 98293-1-RR (same clone as 98293-1-PBS)

    FC experiment of human peripheral blood leukocytes using 98293-1-RR (same clone as 98293-1-PBS)

    1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human CD16a Rabbit RecAb (98293-1-RR, Clone:242426G11) , or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98293-1-PBS in a different storage buffer formulation.

  • FC experiment of human peripheral blood leukocytes using 98293-1-RR (same clone as 98293-1-PBS)

    FC experiment of human peripheral blood leukocytes using 98293-1-RR (same clone as 98293-1-PBS)

    1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human CD16a Rabbit RecAb (98293-1-RR, Clone:242426G11) (red), or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98293-1-PBS in a different storage buffer formulation.

  • 98293-1-RR specifically recognizes human CD16a

    98293-1-RR specifically recognizes human CD16a

    Biolayer interferometry (BLl) kinetic assays of 98293-1-RR against Human CD16a 176F (A), CD16a 176V (B), CD16b NA1 (C) and CD16b NA2 (D) were performed. Affinity constants against two CD16a allotypes are 25.9 nM and 18.3 nM. No binding signal against CD16b allotypes was detected.

  • Affinity and Kinetic Characterization of 98293-1-RR

    Affinity and Kinetic Characterization of 98293-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98293-1-RR against Human CD16a were performed. The affinity constant is 14.3 nM.

Anti-Human CD16a Rabbit Recombinant Antibody, PBS Only

CD16a Uni-rAb® Recombinant Antibody for FC
Cat No. 98293-1-PBS

产品说明书

CloneNo. 242426G11

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

CD16, 242426G11, CD16a antigen, CD16-II, Fc gamma RIII

缓冲液配方:  PBS Only
PBS, Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy CD16 Ready-To-Use IHC Kit. CD16 primary antibody included.

产品信息

98293-1-PBS targets CD16a in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原

CatNo: Eg2488

Product name: recombinant human CD16a protein

Source: mammalian cells-derived, pHZ-KIsec-C-6*HIS

Tag: C-6*HIS

Domain: 10007017 of

Sequence:

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
别名 CD16, 242426G11, CD16a antigen, CD16-II, Fc gamma RIII
计算分子量29 kDa
基因名称 CD16a
Gene ID (NCBI) 2214
ENSEMBL Gene IDENSG00000203747
RRIDAB_3745959
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purfication
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD16 is a 50-70-kDa low affinity Fc receptor found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. CD16 mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. CD16 has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b), encoded by two nearly identical genes, FCGR3A and FCGR3B. This antibody is specific for CD16a and does not recognize CD16b.

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