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验证数据展示

  • FC experiment of mouse bone marrow cells using 98152-1-RR (same clone as 98152-1-PBS)

    FC experiment of mouse bone marrow cells using 98152-1-RR (same clone as 98152-1-PBS)

    1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse CD138/Syndecan-1 Rabbit RecAb (98152-1-RR, Clone: 241278C7) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with APC Anti-Mouse CD19 (1D3) Rat Recombinant Antibody (APC-65661, Clone: 1D3). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98152-1-PBS in a different storage buffer formulation.

  • FC experiment of mouse bone marrow cells using 98152-1-RR (same clone as 98152-1-PBS)

    FC experiment of mouse bone marrow cells using 98152-1-RR (same clone as 98152-1-PBS)

    1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse CD138/Syndecan-1 Rabbit RecAb (98152-1-RR, Clone: 241278C7) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98152-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98152-1-RR

    Affinity and Kinetic Characterization of 98152-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98152-1-RR against Mouse CD138/Syndecan-1 were performed. The affinity constant is 16.5 nM.

Anti-Mouse CD138/Syndecan-1 Rabbit Recombinant Antibody, PBS Only

CD138/Syndecan-1 Uni-rAb® Recombinant Antibody for FC
Cat No. 98152-1-PBS

产品说明书

CloneNo. 241278C7

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

FC

别名

241278C7, CD138, Sdc1, SYND1, Synd-1

缓冲液配方:  PBS Only
PBS, Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

98152-1-PBS targets CD138/Syndecan-1 in FC applications and shows reactivity with mouse samples.

经测试应用 FC Application Description
经测试反应性 mouse
免疫原

CatNo: Eg1221

Product name: Recombinant Mouse CD138/Syndecan-1 protein (His Tag)

Source: mammalian cells-derived, pHZ-KIsec-C-6*HIS

Tag: C-6*HIS

Domain: 23-252 aa of NM_011519.2

Sequence: QIVAVNVPPEDQDGSGDDSDNFSGSGTGALPDTLSRQTPSTWKDVWLLTATPTAPEPTSSNTETAFTSVLPAGEKPEEGEPVLHVEAEPGFTARDKEKEVTTRPRETVQLPITQRASTVRVTTAQAAVTSHPHGGMQPGLHETSAPTAPGQPDHQPPRVEGGGTSVIKEVVEDGTANQLPAGEGSGEQDFTFETSGENTAVAAVEPGLRNQPPVDEGATGASQSLLDRKE

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 syndecan 1
别名 241278C7, CD138, Sdc1, SYND1, Synd-1
计算分子量33 kDa
GenBank蛋白编号NM_011519.2
基因名称 Sdc1
Gene ID (NCBI) 20969
RRIDAB_3672295
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purfication
UNIPROT IDP18828-1
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD138, also named as Syndecan-1 (SDC1), is an integral membrane protein. It participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. It is a heparan sulfate proteoglycan expressed on the surface of, and actively shed by, myeloma cells. Altered syndecan-1 expression has been detected in several different tumor types. CD138 was regarded as a useful marker for labeling normal and neoplastic plasma cells and plasmacytoid lymphomas.

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