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Host
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Species Reactivity
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Species Reactivity
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Conjugate
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验证数据展示

  • FC experiment of human peripheral blood leukocyte using 65563-1-MR (same clone as 65563-1-PBS)

    FC experiment of human peripheral blood leukocyte using 65563-1-MR (same clone as 65563-1-PBS)

    1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human CD11a Mouse IgG2a Recombinant Antibody (65563-1-MR, Clone: TS2/4) or Mouse IgG2a Isotype Control (65208-1-Ig, Clone: C1.18.4), and CoraLite®488-Conjugated AffiniPure Donkey Anti-Mouse IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 65563-1-PBS in a different storage buffer formulation.

Anti-Human CD11a (TS2/4) Mouse IgG2a Recombinant Antibody, PBS Only

CD11a Uni-rAbTM Recombinant Antibody for FC
Cat No. 65563-1-PBS

产品说明书

CloneNo. TS2/4

宿主/亚型

Mouse / IgG2a

种属反应性

human

应用

FC

别名

Leukocyte function-associated molecule 1 alpha chain, Leukocyte adhesion glycoprotein LFA-1 alpha chain, ITGAL, Integrin alpha-L, Integrin alpha L

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

65563-1-PBS targets CD11a in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 HLA-DR CTL line 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Recombinant
产品类型 Antibody
全称 integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
别名 Leukocyte function-associated molecule 1 alpha chain, Leukocyte adhesion glycoprotein LFA-1 alpha chain, ITGAL, Integrin alpha-L, Integrin alpha L
计算分子量 129 kDa
GenBank蛋白编号BC008777
基因名称 CD11a
Gene ID (NCBI) 3683
ENSEMBL Gene IDENSG00000005844
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP20701
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C. Stable for one year after shipment.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD11a, also known as integrin αL or LFA-1α, is a 170-180 kDa transmembrane glycoprotein that forms a heterodimer with CD18 (PMID: 7027264; 1672643). CD11a/CD18 (LFA-1) is expressed by all leukocytes and mediates cell adhesion through interactions with its ligands, intercellular adhesion molecule 1 (ICAM-1), ICAM-2, and ICAM-3 (PMID: 7479767). CD11a/CD18 also functions in lymphocyte costimulatory signaling (PMID: 1972160).