Anti-Mouse CD107b / LAMP2 (ABL-93)

CD107b / LAMP2 Monoclonal Antibody for IF/ICC, FC (Intra)
Cat No. 65052-1-Ig

产品说明书

CloneNo. ABL-93

宿主/亚型

Rat / IgG2a, kappa

种属反应性

Mouse and More (1)

应用

IF/ICC, FC (Intra) and More (1)

CD107b, Lamp2, Mac3, Lamp 2, ABL-93

缓冲液配方:  PBS and Azide
PBS and Azide
规格: 

-/ -


经过测试的应用

Positive IF/ICC detected inNIH/3T3 cells
Positive FC (Intra) detected inNIH/3T3 cells
Positive FC detected inNIH/3T3 cells

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

发表文章中的应用

IFSee 1 publications below

产品信息

65052-1-Ig targets CD107b / LAMP2 in IF/ICC, FC (Intra) applications and shows reactivity with Mouse samples.

经测试应用 IF/ICC, FC (Intra) Application Description
文献引用应用IF
经测试反应性 Mouse
文献引用反应性mouse
免疫原 Glycoproteins purified from BALB/c mouse embryo 3T3 cell line 种属同源性预测
宿主/亚型 Rat / IgG2a, kappa
抗体类别 Monoclonal
产品类型 Antibody
全称 lysosomal-associated membrane protein 2
别名 CD107b, Lamp2, Mac3, Lamp 2, ABL-93
GenBank蛋白编号BC138718
基因名称 CD107b / LAMP2
Gene ID (NCBI) 16784
RRIDAB_2881468
偶联类型 Unconjugated
形式 Liquid
纯化方式Affinity purification
UNIPROT IDP17047
储存缓冲液 PBS with 0.09% sodium azide , pH 7.3
储存条件Store at 2-8°C. Stable for one year after shipment.

背景介绍

LAMP2 (CD107b) is a Lysosomal membrane glycoprotein. LAMP2 is extensively glycosylated with asparagine-linked oligosaccharides which protect it from intracellular proteolysis (PMID: 10521503). Although LAMP-2 is localized primarily in the endosome-lysosomal membrane of cells, it is also found on the plasma membrane under certain circumstances, e.g., after platelet activation, during granulocytic differentiation and activation, and in some tumor cells (PMID: 12221139). LAMP is involved in lysosomal stability and autophagy (PMID: 12221139). This glycoprotein provides selectins with carbohydrate ligands. LAMP2 may plays a role in tumor cell metastasis (PMID 9426697).

实验方案

Product Specific Protocols
IF protocol for CD107b / LAMP2 antibody 65052-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
mouseIF

Cell Rep Med

Targeting phenylpyruvate restrains excessive NLRP3 inflammasome activation and pathological inflammation in diabetic wound healing

Authors - Dongming Lv
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