验证数据展示
经过测试的应用
Positive FC (Intra) detected in | Transfected HEK-293T cells |
推荐稀释比
应用 | 推荐稀释比 |
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Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.25 ug per 10^6 cells in a 100 µl suspension |
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
98464-1-RR targets CCL11/Eotaxin in FC (Intra) applications and shows reactivity with mouse samples.
经测试应用 | FC (Intra) Application Description |
经测试反应性 | mouse |
免疫原 | CCL11/Eotaxin fusion protein Eg2400 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | chemokine (C-C motif) ligand 11 |
别名 | C-C motif chemokine 11, Ccl11, Eosinophil chemotactic protein, Eotaxin, Scya11 |
计算分子量 | 11kd |
GenBank蛋白编号 | NM_011330 |
基因名称 | Ccl11 |
Gene ID (NCBI) | 20292 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P48298 |
储存缓冲液 | PBS with 0.09% sodium azide, pH 7.3. |
储存条件 | Store at 2 - 8°C. Stable for one year after shipment. |
背景介绍
CCL11 also named Eotaxin-1, was initially discovered as an eosinophil-specific chemoattractant. CCL11 plays a central role in both allergic and non-allergic inflammatory reactions by recruiting immune cells such as eosinophils,basophils and Th2 lymphocytes. CCL11 binds to the chemokine receptors CCR2, CCR3 and CCR5, with highest affinity to CCR3. High levels of CCL11 have been described in several chronic inflammatory diseases, such as allergic rhinitis, atopic dermatitis, asthma, gastrointestinal disease and rheumatoid arthritis.
实验方案
Product Specific Protocols | |
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FC protocol for CCL11/Eotaxin antibody 98464-1-RR | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |