验证数据展示
产品信息
31108-1-PBS targets CBX1 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse |
| 免疫原 |
CatNo: Ag34901 Product name: Recombinant human CBX1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 60-115 aa of BC002609 Sequence: CPDLIAEFLQSQKTAHETDKSEGGKRKADSDSEDKGEESKPKKKKEESEKPRGFAR 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | chromobox homolog 1 (HP1 beta homolog Drosophila ) |
| 别名 | CBX, Chromobox protein homolog 1, Heterochromatin protein p25, HP1 beta, HP1Hs beta |
| 计算分子量 | 27 kDa |
| 观测分子量 | 21-27 kDa |
| GenBank蛋白编号 | BC002609 |
| 基因名称 | CBX1 |
| Gene ID (NCBI) | 10951 |
| RRID | AB_3669859 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | P83916 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CBX1 (chromobox 1), also known as CBX. It is expected to be located in nucleus, the protein is expressed in all adult and embryonic tissues. It is a member of the heterochromatin protein family. CBX1 is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. It may play an important role in the epigenetic control of chromatin structure and gene expression. The calculated molecular weight of CBX1 is 21 kDa.

