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验证数据展示

  • FC experiment of human peripheral blood leukocytes using 98226-1-RR (same clone as 98226-1-PBS)

    FC experiment of human peripheral blood leukocytes using 98226-1-RR (same clone as 98226-1-PBS)

    1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human C5AR1/CD88 Rabbit Recombinant Antibody (98226-1-RR, Clone: 241712D4) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with CoraLite® Plus 647 Anti-Human CD16. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98226-1-PBS in a different storage buffer formulation.

  • FC experiment of human peripheral blood leukocytes using 98226-1-RR (same clone as 98226-1-PBS)

    FC experiment of human peripheral blood leukocytes using 98226-1-RR (same clone as 98226-1-PBS)

    1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human C5AR1/CD88 Rabbit Recombinant Antibody (98226-1-RR, Clone: 241712D4) (red) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98226-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98226-1-RR

    Affinity and Kinetic Characterization of 98226-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98226-1-RR against Human C5AR1/CD88 were performed. The affinity constant is 1.56 nM.

Anti-Human C5AR1/CD88 Rabbit Recombinant Antibody, PBS Only

C5AR1/CD88 Uni-rAb® Recombinant Antibody for FC
Cat No. 98226-1-PBS

产品说明书

CloneNo. 241712D4

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

C5AR, C5AR1, 241712D4, C5A, C5a anaphylatoxin chemotactic receptor 1

缓冲液配方:  PBS Only
PBS, Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy C5AR1 Ready-To-Use IHC Kit. C5AR1 primary antibody included.

产品信息

98226-1-PBS targets C5AR1/CD88 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原

CatNo: Eg2185

Product name: Recombinant Human C5AR1/CD88 protein (rFc Tag)

Source: mammalian cells-derived, pHZ-KIsec-C-rFc

Tag: C-rFc

Domain: 1-37 aa of NM_001736.4

Sequence: MDSFNYTTPDYGHYDDKDTLDLNTPVDKTSNTLRVPD

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 complement component 5a receptor 1
别名 C5AR, C5AR1, 241712D4, C5A, C5a anaphylatoxin chemotactic receptor 1
计算分子量39kDa
GenBank蛋白编号NM_001736.4
基因名称 C5aR
Gene ID (NCBI) 728
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purfication
UNIPROT IDP21730
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

C5aR, also named CD88, is a G protein-coupled receptor for the anaphylatoxin C5a, a cleavage product of the complement cascade. The C5a ligand is a proinflammatory component of host defense. C5aR is activated upon binding of the C5a molecule. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release, and superoxide anion production.

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