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验证数据展示

  • WB analysis using 30844-1-AP (same clone as 30844-1-PBS)

    WB analysis using 30844-1-AP (same clone as 30844-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30844-1-AP (C19orf63 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30844-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse kidney using 30844-1-AP (same clone as 30844-1-PBS)

    IHC staining of mouse kidney using 30844-1-AP (same clone as 30844-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 30844-1-AP (C19orf63 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30844-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with C19orf63 antibody included
  • IHC staining of human liver using 30844-1-AP (same clone as 30844-1-PBS)

    IHC staining of human liver using 30844-1-AP (same clone as 30844-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 30844-1-AP (C19orf63 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30844-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with C19orf63 antibody included

C19orf63 Polyclonal antibody, PBS Only

C19orf63 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 30844-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, Indirect ELISA

别名

EMC10, ER Membrane Protein Complex Subunit 10, Hematopoietic signal peptide-containing membrane domain-containing protein 1, HSM1, HSS1

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy® C19orf63 Ready-To-Use IHC Kit. C19orf63 primary antibody included.

产品信息

30844-1-PBS targets C19orf63 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag34064

Product name: Recombinant human C19orf63 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-227 aa of BC035001

Sequence: MAAASAGATRLLLLLLMAVAAPSRARGSGCRAGTGARGAGAEGREGEACGTVGLLLEHSFEIDDSANFRKRGSLLWNQQDGTLSLSQRQLSEEERGRLRDVAALNGLYRVRIPRRPGALDGLEAGGYVSSFVPACSLVESHLSDQLTLHVDVAGNVVGVSVVTHPGGCRGHEVEDVDLELFNTSVQLQPPTTAPGPETAAFIERLEMEQAQKAKNPQEQKSFFAKYW

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 chromosome 19 open reading frame 63
别名 EMC10, ER Membrane Protein Complex Subunit 10, Hematopoietic signal peptide-containing membrane domain-containing protein 1, HSM1, HSS1
观测分子量28 kDa
GenBank蛋白编号BC035001
基因名称 C19orf63
Gene ID (NCBI) 284361
RRIDAB_3742375
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity Purification
UNIPROT IDQ5UCC4
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

EMC10 (Endoplasmic Reticulum Membrane Protein Complex Subunit 10) is one of the key components of the highly conserved endoplasmic reticulum membrane protein complex (EMC). The core function of this complex is to act as an insertase and chaperone in the endoplasmic reticulum, assisting in the correct folding, assembly, and membrane integration of membrane proteins, and preventing the aggregation of misfolded proteins. Studies have shown that EMC10 plays a dual role in cells: within the cell, it ensures the biogenesis of important membrane proteins such as G protein-coupled receptors (GPCRs); moreover, it can be secreted outside the cell (referred to as sEMC10), where it acts as a novel signaling molecule to activate the hypothalamic-pituitary axis, regulating energy metabolism and body weight in the body, and is closely related to obesity and metabolic diseases.

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