验证数据展示
经过测试的应用
| Positive IF-P detected in | human pancreas tissue |
Planning an IHC experiment? We recommend our IHCeasy Insulin Ready-To-Use IHC Kit. Insulin primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 87566-3-PBS
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Immunofluorescence (IF)-P | IF-P : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL488-87566-3 targets C-Peptide in IF-P applications and shows reactivity with human samples.
| 经测试应用 | IF-P Application Description |
| 经测试反应性 | human |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | INS |
| 别名 | INS, insulin |
| 计算分子量 | 110aa, 12 kDa |
| GenBank蛋白编号 | NM_000207 |
| 基因名称 | INS |
| Gene ID (NCBI) | 3630 |
| 偶联类型 | CoraLite® Plus 488 Fluorescent Dye |
| 最大激发/发射波长 | 493 nm / 522 nm |
| 激发激光 | Blue laser (488 nm) |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P01308 |
| 储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| 储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
C‑peptide is a 31‑amino‑acid peptide that connects the A and B chains of proinsulin and is co‑secreted with insulin in equimolar amounts from pancreatic beta cells. With a longer plasma half‑life than insulin, it serves as a reliable biomarker of endogenous insulin secretion. Clinically, measuring C‑peptide is crucial for distinguishing type 1 from type 2 diabetes, diagnosing hypoglycemia, and assessing residual beta‑cell function. Emerging evidence also suggests that C‑peptide may exert its own biological effects on vascular and renal tissues.
实验方案
| Product Specific Protocols | |
|---|---|
| IF protocol for CL Plus 488 C-Peptide antibody CL488-87566-3 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
