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验证数据展示

  • WB analysis using 11613-1-AP (same clone as 11613-1-PBS)

    WB analysis using 11613-1-AP (same clone as 11613-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 11613-1-AP (BCL11A antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11613-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 11613-1-AP (same clone as 11613-1-PBS)

    IHC staining of human tonsillitis using 11613-1-AP (same clone as 11613-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 11613-1-AP (BCL11A antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11613-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with BCL11A antibody included
  • IHC staining of human tonsillitis using 11613-1-AP (same clone as 11613-1-PBS)

    IHC staining of human tonsillitis using 11613-1-AP (same clone as 11613-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 11613-1-AP (BCL11A antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11613-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with BCL11A antibody included
  • IHC staining of human gliomas using 11613-1-AP (same clone as 11613-1-PBS)

    IHC staining of human gliomas using 11613-1-AP (same clone as 11613-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human gliomas tissue slide using 11613-1-AP (BCL11A antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11613-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with BCL11A antibody included
  • IHC staining of human gliomas using 11613-1-AP (same clone as 11613-1-PBS)

    IHC staining of human gliomas using 11613-1-AP (same clone as 11613-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human gliomas tissue slide using 11613-1-AP (BCL11A antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11613-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with BCL11A antibody included
  • IHC staining of mouse spleen using 11613-1-AP (same clone as 11613-1-PBS)

    IHC staining of mouse spleen using 11613-1-AP (same clone as 11613-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse spleen tissue slide using 11613-1-AP (BCL11A antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11613-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with BCL11A antibody included

BCL11A Polyclonal antibody, PBS Only

BCL11A Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 11613-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

B cell lymphoma/leukaemia 11A, B-cell CLL/lymphoma 11A, B-cell lymphoma/leukemia 11A, BCL-11A, COUP-TF-interacting protein 1

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy BCL11A Ready-To-Use IHC Kit. BCL11A primary antibody included.

产品信息

11613-1-PBS targets BCL11A in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag2187

Product name: Recombinant human BCL11A protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-351 aa of BC021098

Sequence: MSRRKQGKPQHLSKREFSPEPLEAILTDDEPDHGPLGAPEGDHDLLTCGQCQMNFPLGDILIFIEHKRKQCNGSLCLEKAVDKPPSPSPIEMKKASNPVEVGIQVTPEDDDCLSTSSRGICPKQEHIADKLLHWRGLSSPRSAHGALIPTPGMSAEYAPQGICKDEPSSYTCTTCKQPFTSAWFLLQHAQNTHGLRIYLESEHGSPLTPRVGIPSGLGAECPSQPPLHGIHIADNNPFNLLRIPGSVSREASGLAEGRFPPTPPLFSPPPRHHLDPHRIERLGAEEMALATHHPSAFDRVLRLNPMAMEPPAMDFSRRLRELAGNTSSPPLSPGRPSPMQRLLQPFQPGSK

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 B-cell CLL/lymphoma 11A (zinc finger protein)
别名 B cell lymphoma/leukaemia 11A, B-cell CLL/lymphoma 11A, B-cell lymphoma/leukemia 11A, BCL-11A, COUP-TF-interacting protein 1
计算分子量 835 aa, 91 kDa
GenBank蛋白编号BC021098
基因名称 BCL11A
Gene ID (NCBI) 53335
RRIDAB_2259028
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9H165
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

B-CELL CLL/LYMPHOMA 11A(BCL11A)is a highly conserved zinc finger gene. It acts as a myeloid and B-cell proto-oncogene, and may play key roles in leukemogenesis and hematopoiesis. It is an essential factor in lymphopoiesis, and required for B-cell formation in fetal liver. May function as a modulator of the transcriptional repression activity of ARP1. It is also involved in lymphoid malignancies through translocation or amplification events. It has recently been shown that BCL11A expression is inversely correlated with γ globin expression.(PMID:21156846). This is a rabbit polyclonal antibody raised against part chain of N-terminal BCL11A of human origin. There are three isoforms of BCL11A: isoform1(773aa), isoform2(486aa) and isoform3(239aa)

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