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Acetyl-Histone H4 (Lys12) Recombinant antibody, PBS Only

Acetyl-Histone H4 (Lys12) Uni-rAbTM Recombinant Antibody for WB, IHC, IF/ICC, Dot Blot, Indirect ELISA
Cat No. 83095-1-PBS

产品说明书

CloneNo. 1D18

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IF/ICC, Dot Blot, Indirect ELISA

Acetyl Histone H4, Ac Histone H4-Lys12, Ac Histone H4 Lys12, Ac Histone H4 (Lys12), Ac Histone H4

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -


产品信息

83095-1-PBS targets Acetyl-Histone H4 (Lys12) in WB, IHC, IF/ICC, Dot Blot, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IF/ICC, Dot Blot, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 Peptide 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 histone cluster 1, H4a
别名 Acetyl Histone H4, Ac Histone H4-Lys12, Ac Histone H4 Lys12, Ac Histone H4 (Lys12), Ac Histone H4
观测分子量12 kDa
GenBank蛋白编号BC069654
基因名称 HIST1H4A
Gene ID (NCBI) 8359
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP62805
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Histone H4 is a 103 amino acid protein, which belongs to the histone H4 family. Histone H4 localizes in the nucleus and is a core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Acetylation of histone H4 is necessary for chromatin decompaction during DNA replication.

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