验证数据展示
产品信息
85402-1-PBS targets AQP2 as part of a matched antibody pair:
MP01925-1: 85402-1-PBS capture and 85402-2-PBS detection (validated in Cytometric bead array)
MP01925-2: 85402-1-PBS capture and 85402-3-PBS detection (validated in Cytometric bead array)
Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.
This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.
经测试应用 | WB, Cytometric bead array, Indirect ELISA Application Description |
经测试反应性 | human, mouse |
免疫原 | AQP2 fusion protein Ag29931 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | aquaporin 2 (collecting duct) |
别名 | Aquaporin 2, AQP-2, Aquaporin2 |
计算分子量 | 29 kDa |
观测分子量 | 28-29, 35-38 kDa |
GenBank蛋白编号 | NM_000486 |
基因名称 | AQP2 |
Gene ID (NCBI) | 359 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P41181 |
储存缓冲液 | PBS only, pH 7.3. |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
AQP2 (Aquaporin2) is a water channel protein that is widely distributed among mammalian tissues and plays a major role in water homeostasis. AQP2 is mainly found in the apical cell membranes of the kidney's collecting duct cells and is critical for urinary concentration. AQP2 can be glycosylated and this antibody recognizes the 28-29 kDa non-glycosylated as well as the 35-40 kDa glycosylated forms of AQP2.