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CoraLite® Plus 488-conjugated AOC3 Monoclonal antibody

AOC3 Monoclonal Antibody for IF-P

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

IF-P

Conjugate

CoraLite® Plus 488 Fluorescent Dye

CloneNo.

2A6G3

Cat No : CL488-66834

Print datasheet

Synonyms

AOC3, Copper amine oxidase, HPAO, Membrane primary amine oxidase, SSAO, VAP 1, VAP1, Vascular adhesion protein 1

验证数据展示

  • IF Staining of human liver cancer using CL488-66834

    IF Staining of human liver cancer using CL488-66834

    Immunofluorescent analysis of (4% PFA) fixed human liver cancer tissue using CoraLite® Plus 488 AOC3 antibody (CL488-66834, Clone: 2A6G3 ) at dilution of 1:200.

  • IF Staining of human liver cancer using CL488-66834

    IF Staining of human liver cancer using CL488-66834

    Immunofluorescent analysis of (4% PFA) fixed human liver cancer tissue using CoraLite® Plus 488 AOC3 antibody (CL488-66834, Clone: 2A6G3 ) at dilution of 1:200.

经过测试的应用

Positive IF detected inhuman liver cancer tissue
For other applications, we recommend the unconjugated version of this antibody, 66834-1-Ig

推荐稀释比

ApplicationDilution
Immunofluorescence (IF)IF : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-66834 targets AOC3 in IF applications and shows reactivity with Human samples.

Tested Applications IF-P
Tested Reactivity Human
Immunogen AOC3 fusion protein Ag5908 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name amine oxidase, copper containing 3 (vascular adhesion protein 1)
Synonyms AOC3, Copper amine oxidase, HPAO, Membrane primary amine oxidase, SSAO, VAP 1, VAP1, Vascular adhesion protein 1
Calculated Molecular Weight 85 kDa
Observed Molecular Weight 85-90 kDa
GenBank Accession NumberBC050549
Gene Symbol AOC3
Gene ID (NCBI) 8639
RRIDAB_2919378
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission Maxima Wavelengths493 nm / 522 nm
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ16853
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Aliquoting is unnecessary for -20oC storage.

背景介绍

AOC3(membrane primary amine oxidase) is also name as copper amine oxidase, HPAO, SSAO, VAP1 and belongs to the copper/topaquinone oxidase family. It is expressed on the surface of endothelial cells and is involved in leukocyte trafficking between blood and tissues under physiologic and pathologic conditions (PMID:17947691). AOC3 is highly expressed in adipocytes and smooth muscle cells and it can be N- and O-glycosylated (PMID:16046623). AOC3 has molecular mass of 70-90kD, and can exsit as a homodimer(165-185kD) and trimer(240~260kD) (PMID:10595925, 8625974).

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 AOC3 antibody CL488-66834Download protocol
Standard Protocols
Click here to view our Standard Protocols