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验证数据展示

  • WB analysis using 32969-1-AP (same clone as 32969-1-PBS)

    WB analysis using 32969-1-AP (same clone as 32969-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 32969-1-AP (ADAM23 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32969-1-PBS in a different storage buffer formulation.

  • WB analysis using 32969-1-AP (same clone as 32969-1-PBS)

    WB analysis using 32969-1-AP (same clone as 32969-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 32969-1-AP (ADAM23 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32969-1-PBS in a different storage buffer formulation.

ADAM23 Polyclonal antibody, PBS Only

ADAM23 Polyclonal Antibody for WB, Indirect ELISA
Cat No. 32969-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, Indirect ELISA

别名

ADAM 23, Disintegrin and metalloproteinase domain-containing protein 23, MDC3, MDC-3, Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

32969-1-PBS targets ADAM23 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag35744

Product name: Recombinant human ADAM23 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 342-488 aa of BC132765

Sequence: NTRVVLVAVETWTEKDQIDITTNPVQMLHEFSKYRQRIKQHADAVHLISRVTFHYKRSSLSYFGGVCSRTRGVGVNEYGLPMAVAQVLSQSLAQNLGIQWEPSSRKPKCDCTESWGGCIMEETGVSHSRKFSKCSILEYRDFLQRGG

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 ADAM metallopeptidase domain 23
别名 ADAM 23, Disintegrin and metalloproteinase domain-containing protein 23, MDC3, MDC-3, Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3
计算分子量 832 aa, 92 kDa
观测分子量92 kDa, 70 kDa
GenBank蛋白编号BC132765
基因名称 ADAM23
Gene ID (NCBI) 8745
RRIDAB_3742807
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity Purification
UNIPROT IDO75077
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ADAM23 (A disintegrin and metalloprotease protein 23), also known as MDC-3 (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) is a transmembrane type I glycoprotein involved with the development and maintenance of the nervous system, including neurite outgrowth, neuronal adhesion and differentiation and regulation of synaptic transmission. In addition, ADAM23 seems to participate in immune response and tumor establishment through interaction with different members of integrin receptors (PMID: 19692335). Two forms of ADAM23 have been previously described in primary cerebellar granule cells as an unprocessed precursor (100 kDa) and mature (70 kDa) protein, respectively (PMID: 29792904).

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