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Species Reactivity
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Conjugate
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验证数据展示

  • FC experiment of human peripheral blood leukocytes using 98329-3-RR

    FC experiment of human peripheral blood leukocytes using 98329-3-RR

    1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human CEACAM6/CD66c Rabbit RecAb (98329-3-RR, Clone: 241997G1) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-conjugated Goat Anti-Rabbit IgG. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

  • FC experiment of human peripheral blood leukocytes using 98329-3-RR

    FC experiment of human peripheral blood leukocytes using 98329-3-RR

    1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human CEACAM6/CD66c Rabbit RecAb (98329-3-RR, Clone:241997G1) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-conjugated Goat Anti-Rabbit IgG. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

Anti-Human CEACAM6/CD66c Rabbit Recombinant Antibody

CEACAM6/CD66c Uni-rAbTM Recombinant Antibody for FC
Cat No. 98329-3-RR

产品说明书

CloneNo. 241997G1

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

CEACAM6, NCA, CEAL, CD66c, Carcinoembryonic antigen-related cell adhesion molecule 6

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格价格库存

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经过测试的应用

Positive FC detected inhuman peripheral blood leukocytes

推荐稀释比

应用推荐稀释比
Flow Cytometry (FC)FC : 0.25 ug per 10^6 cells in 100 μl suspension
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

98329-3-RR targets CEACAM6/CD66c in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
别名 CEACAM6, NCA, CEAL, CD66c, Carcinoembryonic antigen-related cell adhesion molecule 6
计算分子量 37 kDa
GenBank蛋白编号BC005008
基因名称 CEACAM6
Gene ID (NCBI) 4680
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP40199
储存缓冲液 PBS with 0.09% sodium azide, pH 7.3.
储存条件Store at 2 - 8°C. Stable for one year after shipment.

背景介绍

Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) belong to the immunoglobulin superfamily of cell adhesion molecules. CEACAMs play major roles in cell-cell and cell-ECM adhesion and have been implicated in controlling cell proliferation, angiogenesis, and tissue remodeling (PMID: 23021083). CEACAM6, also known as CD66c, is a glycosylphosphatidylinositol (GPI)-linked cell surface protein that belongs to the CEACAM family of the immunoglobulin superfamily (PMID: 23903773). It is normally expressed on the surface of myeloid and epithelial surfaces and upregulated preferentially at the apical/luminal membranes of many tumors (PMID: 27595061; 35082925). CEACAM6 plays an important role in cell adhesion, proliferation, tumorigenesis, metastasis, and immunity (PMID: 31797958).

实验方案

Product Specific Protocols
FC protocol for CEACAM6/CD66c antibody 98329-3-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols