验证数据展示
经过测试的应用
| Positive WB detected in | SK-N-SH cells, U-251 cells |
| Positive IF-P detected in | rat brain tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:2000-1:10000 |
| Immunofluorescence (IF)-P | IF-P : 1:200-1:800 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
85108-5-RR targets SYTL5 in WB, IF-P, ELISA applications and shows reactivity with human, rat samples.
| 经测试应用 | WB, IF-P, ELISA Application Description |
| 经测试反应性 | human, rat |
| 免疫原 | SYTL5 fusion protein Ag21698 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | synaptotagmin-like 5 |
| 别名 | Synaptotagmin-like protein 5, Synaptotagmin like protein 5, synaptotagmin like 5, SLP5, 242838D12 |
| 计算分子量 | 730 aa, 81 kDa |
| 观测分子量 | 82 kDa |
| GenBank蛋白编号 | BC131585 |
| 基因名称 | SYTL5 |
| Gene ID (NCBI) | 94122 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q8TDW5 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
SYTL5, also known as SLP5, is a member of the synaptotagmin-like protein (Slp) family. Members of this family are characterized by the presence of an N-terminal Slp homology domain (SHD), which functions as a Rab27-binding domain, and C-terminal tandem C2 domains, putative Ca(2+)-binding motifs. SYTL5 promotes the development and progression of papillary thyroid carcinoma (PTC) by activating the NF-κB signaling pathway (PMID: 36378561).
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for SYTL5 antibody 85108-5-RR | Download protocol |
| IF protocol for SYTL5 antibody 85108-5-RR | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |