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验证数据展示

  • FC experiment of rat splenocytes using 98250-1-RR

    FC experiment of rat splenocytes using 98250-1-RR

    1x10^6 rat splenocytes were surface stained with 0.25 ug Anti-Rat NKp46/NCR1 Rabbit Recombinant Antibody (98250-1-RR, Clone: 241811E9) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

  • FC experiment of rat splenocytes using 98250-1-RR

    FC experiment of rat splenocytes using 98250-1-RR

    1x10^6 rat splenocytes were surface stained with 0.25 ug Anti-Rat NKp46/NCR1 Rabbit Recombinant Antibody (98250-1-RR, Clone: 241811E9) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

  • Affinity and Kinetic Characterization of 98250-1-RR

    Affinity and Kinetic Characterization of 98250-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98250-1-RR against Rat NKp46/NCR1 were performed. The affinity constant is 0.425 nM.

Anti-Rat NKp46/NCR1 Rabbit Recombinant Antibody

NKp46/NCR1 Uni-rAb® Recombinant Antibody for FC
Cat No. 98250-1-RR

产品说明书

CloneNo. 241811E9

宿主/亚型

Rabbit / IgG

种属反应性

rat

应用

FC

别名

241811E9, Activating receptor 1, Ar1, CD335, Kilr1

缓冲液配方:  PBS, Azide
PBS, Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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经过测试的应用

Positive FC detected inrat splenocytes

推荐稀释比

应用推荐稀释比
Flow Cytometry (FC)FC : 0.25 ug per 10^6 cells in 100 μl suspension
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

98250-1-RR targets NKp46/NCR1 in FC applications and shows reactivity with rat samples.

经测试应用 FC Application Description
经测试反应性 rat
免疫原

CatNo: Eg1469

Product name: Recombinant Rat NKp46/NCR1 protein (rFc Tag)

Source: mammalian cells-derived, pHZ-KIsec-C-rFc

Tag: C-rFc

Domain: 17-258 aa of NM_057199.1

Sequence: QRINTEKQTLPKPIIWAKPSIMVTKGNSVNIWCQGAQSASEYQLYFEGSFFALERPKSSRSMNKVKFFISQMTSHTAGIYTCFYQSGELWSESSNPLKLVVTGLYDTPTLWVHPGPEVTLGENVTFSCHLKTATSKFFLLKERESNHIQHKYGNIQAEFPMGPVTRAHRGTYRCFGSYNDYAWSFPSEPVTLLITGEVENTSLAPTDPVSSLDYWEFDLSTKESGLQKDSAFWDHTAQNLIR

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 natural cytotoxicity triggering receptor 1
别名 241811E9, Activating receptor 1, Ar1, CD335, Kilr1
计算分子量37kDa
GenBank蛋白编号NM_057199.1
基因名称 NKp46/NCR1
Gene ID (NCBI) 117547
RRIDAB_3745917
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDQ9Z0H5
储存缓冲液 PBS with 0.09% sodium azide, pH 7.3.
储存条件Store at 2 - 8°C. Stable for one year after shipment.

背景介绍

NKp46, also known as NCR1 or CD335, is an Ig-like superfamily cell surface receptor that is highly conserved in mammals (PMID: 22021440). NKp46 is a type I transmembrane glycoprotein consisting of two extracellular Ig-like domains, a transmembrane domain, and an intracellular tail (PMID: 9730896). It is expressed on NK cells, rare T-cell subsets and a mucosal population of NKp46+ innate lymphoid cells (PMID: 9730896; 22021440). NKp46 is the major triggering receptor involved in the natural cytotoxicity (PMID: 10359120; 10092106; 15356098).

实验方案

Product Specific Protocols
FC protocol for NKp46/NCR1 antibody 98250-1-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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