验证数据展示
产品信息
27050-1-PBS targets ZRANB1 in IP, Indirect ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | IP, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse |
| 免疫原 |
CatNo: Ag25789 Product name: Recombinant human ZRANB1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-100 aa of AL832925 Sequence: MSERGIKWACEYCTYENWPSAIKCTMCRAQRPSGTIITEDPFKSGSSDVGRDWDPSSTEGGSSPLICPDSSARPRVKSSYSMENANKWSCHMCTYLNWPR 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | zinc finger, RAN-binding domain containing 1 |
| 别名 | hTrabid, TRABID, Ubiquitin thioesterase ZRANB1 |
| 计算分子量 | 81 kDa |
| 观测分子量 | 81 kDa |
| GenBank蛋白编号 | AL832925 |
| 基因名称 | ZRANB1 |
| Gene ID (NCBI) | 54764 |
| RRID | AB_3742213 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9UGI0 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
ZRANB1 is an 81-kDa deubiquitinating enzyme with an Npl14 zinc finger (NZF) domain at the N-terminus and an ovarian tumor (OTU) domain at the C-terminus. ZRANB1 specifically cleaves K29-, K33-, and K63-linked ubiquitin chains, but a mutation of amino acid 443 from cysteine to serine ablates enzymatic activity . (PMID: 36087511, PMID: 34765294)
