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验证数据展示

  • WB analysis using 32519-1-AP (same clone as 32519-1-PBS)

    WB analysis using 32519-1-AP (same clone as 32519-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 32519-1-AP (ZNF280B antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32519-1-PBS in a different storage buffer formulation.

  • IP experiment of K-562 using 32519-1-AP (same clone as 32519-1-PBS)

    IP experiment of K-562 using 32519-1-AP (same clone as 32519-1-PBS)

    IP result of anti-ZNF280B (IP:32519-1-AP, 4ug; Detection:32519-1-AP 1:1500) with K-562 cells lysate 2440 ug. This data was developed using the same antibody clone with 32519-1-PBS in a different storage buffer formulation.

ZNF280B Polyclonal antibody, PBS Only

ZNF280B Polyclonal Antibody for WB, IP, Indirect ELISA
Cat No. 32519-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IP, Indirect ELISA

别名

5'OY11.1, SUHW2, Suppressor of hairy wing homolog 2, Zinc finger protein 279, Zinc finger protein 280B

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

32519-1-PBS targets ZNF280B in WB, IP, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IP, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag38544

Product name: Recombinant human ZNF280B protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 75-268 aa of NM_080764.3

Sequence: YDHLRKDTARKLQPKSHETVTSEAVTVLPASQLESRSTDSPIIIEPLSKPDYRNSSPQVVPNNSSELPSPLITFTDSLHHPVSTALSVGGINESPRVSKQLSTFEVNSINPKRAKLRDGIIEGNSSASFPSDTFHTMNTQQSTPSNNVHTSLSHVQNGAPFPAAFPKDNIHFKPINTNLDRANELAKTDILSLT

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 zinc finger protein 280B
别名 5'OY11.1, SUHW2, Suppressor of hairy wing homolog 2, Zinc finger protein 279, Zinc finger protein 280B
计算分子量62kDa，543aa
观测分子量60 kDa
GenBank蛋白编号NM_080764.3
基因名称 ZNF280B
Gene ID (NCBI) 140883
RRIDAB_3742641
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity Purification
UNIPROT IDQ86YH2
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ZNF280B belongs to the family of zinc finger proteins, a transcription factor that is mainly involved in the regulation of gene expression. In prostate cancer cells, ZNF280B induces p53 nuclear export, leading to subsequent proteasomal degradation. Therefore, ZNF280B has pro-growth and pro-survival functions in prostate cancer cells. In addition to this, ZNF280B has a promotional role in gastric and lung cancer development, and its potential as a tumor therapeutic target can be explored in the future.

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