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验证数据展示

  • WB analysis of mouse liver using 55156-1-AP (same clone as 55156-1-PBS)

    WB analysis of mouse liver using 55156-1-AP (same clone as 55156-1-PBS)

    mouse liver tissue were subjected to SDS PAGE followed by western blot with 55156-1-AP (XDH Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55156-1-PBS in a different storage buffer formulation.

  • IHC staining of human heart using 55156-1-AP (same clone as 55156-1-PBS)

    IHC staining of human heart using 55156-1-AP (same clone as 55156-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human heart using 55156-1-AP (XDH antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 55156-1-PBS in a different storage buffer formulation.

  • IHC staining of human heart using 55156-1-AP (same clone as 55156-1-PBS)

    IHC staining of human heart using 55156-1-AP (same clone as 55156-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human heart using 55156-1-AP (XDH antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 55156-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

XDH Polyclonal antibody, PBS Only

XDH Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 55156-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

xanthine dehydrogenase, Xanthine Oxidase, Xanthine oxidoreductase, XD, XDHA

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

55156-1-PBS targets XDH in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

Peptide

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 xanthine dehydrogenase
别名 xanthine dehydrogenase, Xanthine Oxidase, Xanthine oxidoreductase, XD, XDHA
计算分子量 146 kDa
观测分子量 147-150 kDa
GenBank蛋白编号NM_000379
基因名称 XDH
Gene ID (NCBI) 7498
RRIDAB_10860905
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDP47989
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

XDH, also named as XDHA, XO and XD, belongs to the xanthine dehydrogenase family. It catalyzes the last two steps of purine catabolism in man, formation of the end product uric acid from hypoxanthine and xanthine. The mammalian enzyme is synthesized as a dehydrogenase (XDH), which uses NAD as the electron acceptor, but it can be converted into an oxidase (XO) both in vivo and in vitro.This gene encodes a protein of 150 kDa and the 150 kDa polypeptide can be processed into a fragment of 130 kDa and further to 85 kDa by spontaneous proteolytic cleavage(PMID:9989587). In addition, the full length polypeptide can be also partially processed into a 87 kDa and 59 kDa fragments(PMID:21528298). It also can exsit as a homodimer(PMID:9989587).

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