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FRMD6/Willin Polyclonal antibody, PBS Only

FRMD6/Willin Polyclonal Antibody for WB, IHC, FC (Intra), Indirect ELISA
Cat No. 21039-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, FC (Intra), Indirect ELISA

FRMD6, Willin, EX1, FERM domain containing 6, FERM domain-containing protein 6

缓冲液配方:  PBS Only
偶联物:  Unconjugated
规格价格库存


产品信息

21039-1-PBS targets FRMD6/Willin in WB, IHC, FC (Intra), Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, FC (Intra), Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag15375

Product name: Recombinant human Willin protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-266 aa of BC029870

Sequence: LDMDQLEKRSRASGSSAGSMKHKRLSRHSTASHSSSHTSGIEADTKPRDTGPEDSYSSSAIHRKLKTCSSMTSHGSSHTSGVESGGKDRLEEDLQDDEIEMLVDDPRDLEQMNEESLEVSPDMCIYITEDMLMSRKLNGHSGLIVKEIGSSTSSSSETVVKLRGQSTDSLPQTICRKPKTSTDRHSLSLDDIRLYQKDFLRIAGLCQDTAQSYTFGCGHELDEEGLYCNSCLAQQCINIQDAFPVKRTSKYFSLDLTHDEVPEFVV

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 FERM domain containing 6
别名 FRMD6, Willin, EX1, FERM domain containing 6, FERM domain-containing protein 6
计算分子量 622 aa, 72 kDa
观测分子量72, 70, 30 kDa
GenBank蛋白编号BC029870
基因名称 FRMD6/Willin
Gene ID (NCBI) 122786
RRIDAB_2878797
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ96NE9
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Willin, also known as FRMD6 or human Expanded (hEx), is a member of the FERM-domain family of cytoskeletal crosslinkers. It is a potent inhibitor of cell proliferation, transformation and modulator of drug sensitivity, suggesting it possesses tumor suppressor properties. Willin is widely expressed in normal tissues. Although willin is found in the cytoplasm and membrane, it localizes to the nuclei of almost all tumors.This antibody was raised against the C-terminal region of human FRMD6 protein and is expected to recognize the endogenous FRMD6.

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