验证数据展示
产品信息
66432-1-Ig targets WNT1 in ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 | WNT1 fusion protein Ag25463 种属同源性预测 |
| 宿主/亚型 | Mouse / IgG2a |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | wingless-type MMTV integration site family, member 1 |
| 别名 | INT1, Proto oncogene Int 1 homolog, Proto oncogene Wnt 1, WNT1 |
| 观测分子量 | 41 kDa |
| GenBank蛋白编号 | BC074799 |
| 基因名称 | WNT1 |
| Gene ID (NCBI) | 7471 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P04628 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
WNT1 is a member of the WNT gene family. WNT1 have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome.