验证数据展示
产品信息
26701-1-PBS targets WDR35 in IF/ICC, Indirect ELISA applications and shows reactivity with human, canine samples.
| 经测试应用 | IF/ICC, Indirect ELISA Application Description |
| 经测试反应性 | human, canine |
| 免疫原 |
CatNo: Ag24965 Product name: Recombinant human WDR35 protein Source: e coli.-derived, PET30a Tag: 6*His Domain: 822-1170 aa of BC036659 Sequence: AECYYMLEDYEGLENLAISLPENHKLLPEIAQMFVRVGMCEQAVTTFLKCSQPKAAVDTCVHLNQWNKAVELAKNHSMKEIGSLLARYASHLLEKNKTLDAIELYRKANYFFDAAKLMFKIADEEAKKGSKPLRVKKLYVLSALLIEQYHEQMKNAQRGKVKGKSSEATSALAGLLEEEVLSTTDRFTDNAWRGAEAYHFFILAQRQLYEGCVDTALKTALHLKDYEDIIPPVEIYSLLALCACAGRAFGTCSKAFIKLKSLETLSSEQKQQYEDLALEIFTKHTSKDNRKPELDSLMEGGEGKLPTCVATGSPITEYQFWMCSVCKHGVLAQEISHYSFCPLCHSPVG 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | WD repeat domain 35 |
| 别名 | |
| 计算分子量 | 1170 aa, 132 kDa |
| GenBank蛋白编号 | BC036659 |
| 基因名称 | WDR35 |
| Gene ID (NCBI) | 57539 |
| RRID | AB_3085893 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9P2L0 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
WDR35, a component of the IFT complex A (IFT-A), is required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs). It is involved in ciliogenesis and ciliary protein trafficking (PMID:21473986, PMID:28400947, PMID:29220510). It may promote CASP3 activation and TNF-stimulated apoptosis (PMID: 20193664).

