Anti-Human VEGFR2/CD309 Rabbit Recombinant Antibody

VEGFR2/CD309 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98009-1-RR

产品说明书

CloneNo. 230238B11

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

KDR, VEGFR2, VEGFR2/KDR, 230238B11, CD309

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
CoraLite®594
规格价格库存


经过测试的应用

Positive FC detected inHUVEC cells

推荐稀释比

应用推荐稀释比
Flow Cytometry (FC)FC : 0.25 ug per 10^6 cells in a 100 µl suspension
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

98009-1-RR targets VEGFR2/CD309 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 VEGFR2/CD309 fusion protein Eg0218 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 kinase insert domain receptor (a type III receptor tyrosine kinase)
别名 KDR, VEGFR2, VEGFR2/KDR, 230238B11, CD309
计算分子量 152 kDa
GenBank蛋白编号NM_002253
基因名称 KDR
Gene ID (NCBI) 3791
RRIDAB_3672151
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP35968-1
储存缓冲液 PBS with 0.09% sodium azide, pH 7.3.
储存条件Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

背景介绍

VEGFR2, also named as CD309, KDR and FLK1, is a receptor for VEGF or VEGFC. VEGFR2 which belongs to the protein kinase superfamily, has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. VEGFR2 functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. Mutations of this gene are implicated in infantile capillary hemangiomas.

实验方案

Product Specific Protocols
FC protocol for VEGFR2/CD309 antibody 98009-1-RRDownload protocol
Standard Protocols
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