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验证数据展示

  • WB analysis using 21492-1-AP (same clone as 21492-1-PBS)

    WB analysis using 21492-1-AP (same clone as 21492-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 21492-1-AP (VANGL2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21492-1-PBS in a different storage buffer formulation.

  • IP experiment of HepG2 using 21492-1-AP (same clone as 21492-1-PBS)

    IP experiment of HepG2 using 21492-1-AP (same clone as 21492-1-PBS)

    IP result of anti-VANGL2 (IP:21492-1-AP, 4ug; Detection:21492-1-AP 1:500) with HepG2 cells lysate 1880 ug. This data was developed using the same antibody clone with 21492-1-PBS in a different storage buffer formulation.

  • IHC staining of human stomach using 21492-1-AP (same clone as 21492-1-PBS)

    IHC staining of human stomach using 21492-1-AP (same clone as 21492-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human stomach tissue slide using 21492-1-AP (VANGL2 antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 21492-1-PBS in a different storage buffer formulation.

  • IHC staining of human stomach using 21492-1-AP (same clone as 21492-1-PBS)

    IHC staining of human stomach using 21492-1-AP (same clone as 21492-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human stomach tissue slide using 21492-1-AP (VANGL2 antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 21492-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

VANGL2 Polyclonal antibody, PBS Only

VANGL2 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA
Cat No. 21492-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IP, Indirect ELISA

别名

KIAA1215, Loop tail protein 1 homolog, Loop-tail protein 1 homolog, LPP1, LTAP

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

21492-1-PBS targets VANGL2 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IP, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag15833

Product name: Recombinant human VANGL2 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 268-322 aa of BC103920

Sequence: IQRVAVWILEKYYHDFPVYNPALLNLPKSVLAKKVSGFKVYSLGEENSTNNSTGQ

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 vang-like 2 (van gogh, Drosophila)
别名 KIAA1215, Loop tail protein 1 homolog, Loop-tail protein 1 homolog, LPP1, LTAP
计算分子量 521 aa, 60 kDa
观测分子量 60-70 kDa
GenBank蛋白编号BC103920
基因名称 VANGL2
Gene ID (NCBI) 57216
RRIDAB_11182263
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9ULK5
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Vangl2 is a key component of the planar cell polarity (PCP) pathway. Vangl2 is tightly associated with the postsynaptic density (PSD) fraction and forms a protein complex with PSD-95 and NMDA receptors. Vangl2 directly binds to the third PDZ domain of PSD-95 via its C-terminal TSV motif. Vangl2 directly binds to N-cadherin.

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