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Host
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Species Reactivity
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Species Reactivity
0
Conjugate
0
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Compatible Species
0
Conjugate
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验证数据展示

  • WB analysis using 85597-4-RR (same clone as 85597-4-PBS)

    WB analysis using 85597-4-RR (same clone as 85597-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85597-4-RR (Umod antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85597-4-PBS in a different storage buffer formulation.

  • IHC staining of mouse kidney using 85597-4-RR (same clone as 85597-4-PBS)

    IHC staining of mouse kidney using 85597-4-RR (same clone as 85597-4-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 85597-4-RR (Uromodulin antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85597-4-PBS in a different storage buffer formulation.

  • IF Staining of mouse kidney using 85597-4-RR (same clone as 85597-4-PBS)

    IF Staining of mouse kidney using 85597-4-RR (same clone as 85597-4-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse kidney tissue using Uromodulin antibody (85597-4-RR, Clone: 242258H4 ) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85597-4-PBS in a different storage buffer formulation.

  • IF Staining of mouse kidney using 85597-4-RR (same clone as 85597-4-PBS)

    IF Staining of mouse kidney using 85597-4-RR (same clone as 85597-4-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse kidney tissue using Uromodulin antibody (85597-4-RR, Clone: 242258H4 ) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85597-4-PBS in a different storage buffer formulation.

Mouse Uromodulin Recombinant antibody, PBS Only

Uromodulin Uni-rAbTM Recombinant Antibody for WB, IHC, IF-P, Indirect ELISA
Cat No. 85597-4-PBS

产品说明书

CloneNo. 242258H4

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

WB, IHC, IF-P, Indirect ELISA

别名

Tamm-Horsfall urinary glycoprotein, THP, Umod, Uromodulin, secreted form

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

85597-4-PBS targets Uromodulin in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with mouse samples.

经测试应用 WB, IHC, IF-P, Indirect ELISA Application Description
经测试反应性 mouse
免疫原 Uromodulin fusion protein Eg2748 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 Uromodulin
别名 Tamm-Horsfall urinary glycoprotein, THP, Umod, Uromodulin, secreted form
计算分子量71 kDa
观测分子量110 kDa
GenBank蛋白编号NM_009470.5
基因名称 Umod
Gene ID (NCBI) 22242
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ91X17
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Uromodulin, also known as THP (Tamm-Horsfall glycoprotein), is the most abundant protein excreted in the urine under physiological conditions. Uromodulin is synthesized by the kidney and localizes in cells lining the ascending limb of Henle and distal convoluted tubule. Uromodulin is linked to water/electrolyte balance and kidney innate immunity. Also, studies in knockout mice demonstrated that it has a protective role against urinary tract infections and renal stone formation. Mutations in the gene encoding uromodulin lead to rare autosomal dominant diseases, collectively referred to as uromodulin-associated kidney diseases. (PMID: 21654721)