验证数据展示
产品信息
32375-1-PBS targets USP43 in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag36448 Product name: Recombinant human USP43 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 900-1123 aa of BC136368 Sequence: CLAPGNSDGPNTARKLKENAGQDIKLPRKFDLPLTVMPSVEHEKPARPEGQKAMNWKESFQMGSKSSPPSPYMGFSGNSKDSRRGTSELDRPLQGTLTLLRSVFRKKENRRNERAEVSPQVPPVSLVSGGLSPAMDGQAPGSPPALRIPEGLARGLGSRLERDVWSAPSSLRLPRKASRAPRGSALGMSQRTVPGEQASYGTFQRVKYHTLSLGRKKTLPESSF 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | ubiquitin specific peptidase 43 |
| 别名 | Deubiquitinating enzyme 43, EC:3.4.19.12, Ubiquitin carboxyl-terminal hydrolase 43, Ubiquitin thioesterase 43, Ubiquitin-specific-processing protease 43 |
| 观测分子量 | 70 kDa |
| GenBank蛋白编号 | BC136368 |
| 基因名称 | USP43 |
| Gene ID (NCBI) | 124739 |
| RRID | AB_3742585 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | Q70EL4 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
USP43 belongs to the DUBs family involved in cancer development and progression.The USPs family is the most recognized group of DUBs, characterized by a wide range of structural and functional variability. The distinguishing features of USPs include the unique catalytic core, known as the histidine and cysteine boxes, as well as the presence of zinc finger domains, ubiquitin-binding domains, or ubiquitin-like domains at the N and/or Ctermini of the catalytic domain (PMID: 16325574). It has 4 isoforms with a molecular weight of 69 kDa, 89 kDa,122 kDa, 123 kDa.
