验证数据展示
产品信息
15000-1-PBS targets UNKL in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 |
CatNo: Ag6990 Product name: Recombinant human UNKL protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-229 aa of BC000150 Sequence: MTCCSQVPPRRRPSLALSPRLDCNGLNGVPGSIWDFVSGSFSPSPSPILSAGPPSSSSASPNGAELARVRRQLDEAKRKIRQWEESWQQVKQVCDAWQREAQEAKERARVADSDRQLALQKKEEVEAQVKQLQEELEGLGVASTLPGLRGCGDIGTIPLPKLHSLQSQLRLDLEAVDGVIFQLRAKQCVACRERAHGAVLRPCQHHILCEPCAATAPECPYCKGQPLQW 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | unkempt homolog (Drosophila)-like |
| 别名 | C16orf28, EC:2.3.2.-, KIAA0734, Putative E3 ubiquitin-protein ligase UNKL, RING finger protein unkempt-like |
| 计算分子量 | 25 kDa |
| 观测分子量 | 32 kDa, 45 kDa |
| GenBank蛋白编号 | BC000150 |
| 基因名称 | UNKL |
| Gene ID (NCBI) | 64718 |
| RRID | AB_2213189 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9H9P5 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Putative E3 ubiquitin-protein ligase UNKL was expressed at significantly lower levels in endometrial tumor tissues as compared to the endometrium. Importantly, in human endometrial cancer, primary tumor expression of UNKL was correlated with overall survival in black patients with high mutational burden.
