验证数据展示
产品信息
21839-1-PBS targets UNC13B in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 |
CatNo: Ag16478 Product name: Recombinant human UNC13B protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-330 aa of BC111781 Sequence: MSLLCVRVKRAKFQGSPDKFNTYVTLKVQNVKSTTVAVRGDQPSWEQDFMFEISRLDLGLSVEVWNKGLIWDTMVGTVWIALKTIRQSDEEGPGEWSTLEAETLMKDDEICGTRNPTPHKILLDTRFELPFDIPEEEARYWTYKWEQINALGADNEYSSQEESQRKPLPTAAAQCSFEDPDSAVDDRDSDYRSETSNSFPPPYHTASQPNASVHQFPVPVRSPQQLLLQGSSRDSCNDSMQSYDLDYPERRAISPTSSSRYGSSCNVSQGSSQLSELDQYHEQDDDHRETDSIHSCHSSHSLSRDGQAGFGEQEKPLEVTGQAEKEAACE 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | unc-13 homolog B (C. elegans) |
| 别名 | unc-13 homolog B , Protein unc-13 homolog B, Munc13-2 |
| 计算分子量 | 1610 aa, 183 kDa |
| 观测分子量 | 180 kDa |
| GenBank蛋白编号 | BC111781 |
| 基因名称 | UNC13B |
| Gene ID (NCBI) | 10497 |
| RRID | AB_3669376 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | O14795 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
UNC13A is a member of the unliganded-13 (UNC13) family and plays a crucial role in synaptic vesicle priming and exocytosis. UNC13B has been implicated in autism spectrum disorder (ASD), partial epilepsy, and schizophrenia (PMID: 38188011).
