验证数据展示
经过测试的应用
| Positive WB detected in | HEK-293 cells, mouse brain tissue, HeLa cells, SH-SY5Y cells, rat brain tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
21839-1-AP targets UNC13B in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 | UNC13B fusion protein Ag16478 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | unc-13 homolog B (C. elegans) |
| 别名 | unc-13 homolog B , Protein unc-13 homolog B, Munc13-2 |
| 计算分子量 | 1610 aa, 183 kDa |
| 观测分子量 | 180 kDa |
| GenBank蛋白编号 | BC111781 |
| 基因名称 | UNC13B |
| Gene ID (NCBI) | 10497 |
| RRID | AB_3669376 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | O14795 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
UNC13A is a member of the unliganded-13 (UNC13) family and plays a crucial role in synaptic vesicle priming and exocytosis. UNC13B has been implicated in autism spectrum disorder (ASD), partial epilepsy, and schizophrenia (PMID: 38188011).
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for UNC13B antibody 21839-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
