验证数据展示
产品信息
14457-1-PBS targets UGT1A10 in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag6052 Product name: Recombinant human UGT1A10 protein Source: e coli.-derived, PKG Tag: GST Domain: 1-350 aa of BC053576 Sequence: MARAGWTSPVPLCVCLLLTCGFAEAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVVVVMPEVSWQLERSLNCTVKTYSTSYTLEDQNREFMVFAHAQWKAQAQSIFSLLMSSSSGFLDLFFSHCRSLFNDRKLVEYLKESSFDAVFLDPFDTCGLIVAKYFSLPSVVFTRGIFCHHLEEGAQCPAPLSYVPNDLLGFSDAMTFKERVWNHIVHLEDHLFCQYLFRNALEIASEILQTPVTAYDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCHQGKPLPMEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVK 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | UDP glucuronosyltransferase 1 family, polypeptide A10 |
| 别名 | |
| 计算分子量 | 60 kDa |
| 观测分子量 | 60 kDa |
| GenBank蛋白编号 | BC053576 |
| 基因名称 | UGT1A10 |
| Gene ID (NCBI) | 54575 |
| RRID | AB_3669187 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9HAW8 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
UGT1A10 belongs to the superfamily of UDP-glucuronosyltransferases (UGTs) catalyzing the glucuronidation reaction, which is important in the detoxification and enhanced elimination of many endogenous and exogenous substrates. Recently, UGT1A10 was the only enzyme in all 19 known human UGTs to catalyze DA glucuronidation. The UGT1As, among three subfamilies (1A, 2A, and 2B) found in human, share a common C-terminal domain of 245 residues. The N-terminal domains that determine their substrate-binding specificity are variable.
