验证数据展示
产品信息
67318-1-PBS targets UBP1 in WB, Indirect ELISA applications and shows reactivity with Human samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | Human |
免疫原 | UBP1 fusion protein Ag5010 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | upstream binding protein 1 (LBP-1a) |
别名 | DKFZp686L1745, LBP 1a, LBP 1B, LBP1, LBP1A, LBP1B, Transcription factor LBP 1, UBP1, Upstream binding protein 1 |
计算分子量 | 60 kDa |
观测分子量 | 65-68 kDa |
GenBank蛋白编号 | BC047235 |
基因名称 | UBP1 |
Gene ID (NCBI) | 7342 |
RRID | AB_2882578 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | Q9NZI7 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
UBP1, also known as Transcription factor LBP-1, is a 540 amino acid protein, which is expressed in adrenal tissue, JEG-3, NCI-H295A, Hep-G2 and HeLa cell lines. UBP1 localizes in nuclear and can be induced by HIV-1 infection of lymphocytes. UBP1 functions as a transcriptional activator in a promoter context-dependent manner and modulates the placental expression of CYP11A1. UBP1 is involved in regulation of the alpha-globin gene in erythroid cells and represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.