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验证数据展示

  • WB analysis of human placenta using 86010-2-RR (same clone as 86010-2-PBS)

    WB analysis of human placenta using 86010-2-RR (same clone as 86010-2-PBS)

    human placenta tissue were subjected to SDS PAGE followed by western blot with 86010-2-RR (TEK antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86010-2-PBS in a different storage buffer formulation.

  • WB analysis of HUVEC using 86010-2-RR (same clone as 86010-2-PBS)

    WB analysis of HUVEC using 86010-2-RR (same clone as 86010-2-PBS)

    HUVEC cells were subjected to SDS PAGE followed by western blot with 86010-2-RR (TEK antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86010-2-PBS in a different storage buffer formulation.

Tie-2/CD202b Recombinant antibody, PBS Only

Tie-2/CD202b Recombinant Antibody for WB, Indirect ELISA
Cat No. 86010-2-PBS

产品说明书

CloneNo. 250234F8

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Indirect ELISA

别名

TEK, Angiopoietin 1 receptor, Angiopoietin-1 receptor, CD202B, EC:2.7.10.1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

86010-2-PBS targets Tie-2/CD202b in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原 Tie-2/CD202b fusion protein Eg3367 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 TEK tyrosine kinase, endothelial
别名 TEK, Angiopoietin 1 receptor, Angiopoietin-1 receptor, CD202B, EC:2.7.10.1
计算分子量 1124 aa, 126 kDa
观测分子量120 kDa, 160 kDa
GenBank蛋白编号BC035514
基因名称 Tie2
Gene ID (NCBI) 7010
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDQ02763
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Tie2 (also known as TEK) is a tyrosine-protein kinase expressed almost exclusively on endothelial cells. It contains two immunoglobulin-like domains, three epidermal growth factor (EGF)--like domains and three fibronectin type III repeats. Tie2 acts as a cell-surface receptor for ANGPT1, ANGPT2, and ANGPT4 and regulates angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. Mutations in the gene Tie2 are associated with inherited venous malformations of the skin and mucous membranes. Human Tie2 has a calculated molecular weight of 126 kDa. As a result of glycosylation, the apparent molecular mass of Tie2 is approximately 140-160 kDa.