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验证数据展示

  • WB analysis of H69/H146 cells using 21696-1-AP (same clone as 21696-1-PBS)

    WB analysis of H69/H146 cells using 21696-1-AP (same clone as 21696-1-PBS)

    WB result of anti-ODZ1 (21696-1-AP) with two cell lines by Dr. Petrini, Iacopo. This data was developed using the same antibody clone with 21696-1-PBS in a different storage buffer formulation.

  • WB analysis using 21696-1-AP (same clone as 21696-1-PBS)

    WB analysis using 21696-1-AP (same clone as 21696-1-PBS)

    Various lysates were subjected to SDS page followed by western blot with 21696-1-AP (ODZ1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21696-1-PBS in a different storage buffer formulation.

  • IHC staining of human brain using 21696-1-AP (same clone as 21696-1-PBS)

    IHC staining of human brain using 21696-1-AP (same clone as 21696-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 21696-1-AP (ODZ1 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21696-1-PBS in a different storage buffer formulation.

  • IHC staining of human brain using 21696-1-AP (same clone as 21696-1-PBS)

    IHC staining of human brain using 21696-1-AP (same clone as 21696-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 21696-1-AP (ODZ1 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21696-1-PBS in a different storage buffer formulation.

Teneurin 1 Polyclonal antibody, PBS Only

Teneurin 1 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 21696-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

ODZ1, Protein Odd Oz/ten-m homolog 1, Ten 1, TEN M1, Ten-1

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

21696-1-PBS targets Teneurin 1 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag16289

Product name: Recombinant human ODZ1 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-280 aa of BC140783

Sequence: MEQTDCKPYQPLPKVKHEMDLAYTSSSDESEDGRKPRQSYNSRETLHEYNQELRMNYNSQSRKRKEVEKSTQEMEFCETSHTLCSGYQTDMHSVSRHGYQLEMGSDVDTETEGAASPDHALRMWIRGMKSEHSSCLSSRANSALSLTDTDHERKSDGENGFKFSPVCCDMEAQAGSTQDVQSSPHNQFTFRPLPPPPPPPHACTCARKPPPAADSLQRRSMTTRSQPSPAAPAPPTSTQDSVHLHNSWVLNSNIPLETRHFLFKHGSGSSAIFSAASQNY

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 odz, odd Oz/ten-m homolog 1(Drosophila)
别名 ODZ1, Protein Odd Oz/ten-m homolog 1, Ten 1, TEN M1, Ten-1
计算分子量 2732 aa, 306 kDa
观测分子量305 kDa
GenBank蛋白编号BC140783
基因名称 Teneurin 1
Gene ID (NCBI) 10178
RRIDAB_10858625
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9UKZ4
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ODZ1 (also known as teneurin-1, TENM1), which plays a key role in central nervous system ontogenesis. ODZ1 is upregulated in Glioblastoma cells through a Stat3-mediated pathway activated by IL-6, which is released by tumor-associated monocytes. In addition, a hypoxic microenvironment regulates GBM tumor cell migration in part by inducing ODZ1 through hypomethylation of a CpG island in the ODZ1 promoter.

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