验证数据展示
产品信息
27617-1-PBS targets TSPYL5 in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag26314 Product name: Recombinant human TSPYL5 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-210 aa of BC045630 Sequence: MSGRSRGRKSSRAKNRGKGRAKARVRPAPDDAPRDPDPSQYQSLGEDTQAAQVQAGAGWGGLEAAASAQLLRLGEEAACRLPLDCGLALRARAAGDHGQAAARPGPGKAASLSERLAADTVFVGTAGTVGRPKNAPRVGNRRGPAGKKAPETCSTAGRGPQVIAGGRQKKGAAGENTSVSAGEEKKEERDAGSGPPATEGSMDTLENVQL 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | TSPY-like 5 |
| 别名 | KIAA1750, TSPY like 5, TSPY like protein 5 |
| 计算分子量 | 417 aa, 45 kDa |
| 观测分子量 | 45-50 kDa |
| GenBank蛋白编号 | BC045630 |
| 基因名称 | TSPYL5 |
| Gene ID (NCBI) | 85453 |
| RRID | AB_3742244 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q86VY4 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
TSPYL5 (Testis-specific Y-encoded-like protein 5) is involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. It is also involved in the regulation of p53/TP53, and suppresses p53/TP53 protein levels and promotes its ubiquitination; Its function is dependent on USP7 and independent on MDM2 (PMID: 20079711; 21170034).
