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验证数据展示

  • IP experiment of mouse kidney using 13411-1-AP (same clone as 13411-1-PBS)

    IP experiment of mouse kidney using 13411-1-AP (same clone as 13411-1-PBS)

    IP result of anti-TRPV6 (IP:13411-1-AP, 4ug; Detection:13411-1-AP 1:300) with mouse kidney tissue lysate 4000ug. This data was developed using the same antibody clone with 13411-1-PBS in a different storage buffer formulation.

  • WB analysis of human placenta using 13411-1-AP (same clone as 13411-1-PBS)

    WB analysis of human placenta using 13411-1-AP (same clone as 13411-1-PBS)

    human placenta tissue were subjected to SDS PAGE followed by western blot with 13411-1-AP (TRPV6 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13411-1-PBS in a different storage buffer formulation.

  • IF Staining of HeLa using 13411-1-AP (same clone as 13411-1-PBS)

    IF Staining of HeLa using 13411-1-AP (same clone as 13411-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using TRPV6 antibody (13411-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 13411-1-PBS in a different storage buffer formulation.

TRPV6 Polyclonal antibody, PBS Only

TRPV6 Polyclonal Antibody for WB, IF/ICC, IP, Indirect ELISA
Cat No. 13411-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IF/ICC, IP, Indirect ELISA

别名

CATL, CaT1, CaT like, CaT L, Calcium transport protein 1

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

13411-1-PBS targets TRPV6 in WB, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IF/ICC, IP, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag4060

Product name: Recombinant human TRPV6 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-106 aa of BC034814

Sequence: MYVENHCSRPALLLQLWGRGSPAQARGWQGVRNSPVACSSPFRQEHCMSEHFKNRPACLGARSPPQGHKWGESPSQGTQAGAGKCRACGKRVSEGDRNGSGGGKWG

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 transient receptor potential cation channel, subfamily V, member 6
别名 CATL, CaT1, CaT like, CaT L, Calcium transport protein 1
计算分子量 725 aa, 83 kDa
观测分子量 83 kDa, 70 kDa
GenBank蛋白编号BC034814
基因名称 TRPV6
Gene ID (NCBI) 55503
RRIDAB_2272390
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9H1D0
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TRPV6, also named as CAT1 or ECaC2, is a member of the transient receptor potential (TRP) family of membrane proteins. Unlike most TRP channels, TRPV6 and its closest relative, TRPV5, are calcium-selective channels. TRPV6 is highly expressed in the proximal intestine, placenta and exocrine tissues (PMID: 12869611). It is probably involved in calcium absorption in various tissues, including calcium reabsorption in kidney. TRPV6 is overexpressed in some cancers and exhibits oncogenic potential.

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