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验证数据展示

  • WB analysis using 31976-1-AP (same clone as 31976-1-PBS)

    WB analysis using 31976-1-AP (same clone as 31976-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 31976-1-AP (TRIML2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31976-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse testis using 31976-1-AP (same clone as 31976-1-PBS)

    IHC staining of mouse testis using 31976-1-AP (same clone as 31976-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 31976-1-AP (TRIML2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31976-1-PBS in a different storage buffer formulation.

TRIML2 Polyclonal antibody, PBS Only

TRIML2 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 31976-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, Indirect ELISA

别名

EC:2.3.2.27, Probable E3 ubiquitin-protein ligase TRIML2, RING-type E3 ubiquitin transferase TRIML2, SPRY domain-containing protein 6, SPRYD6

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

31976-1-PBS targets TRIML2 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag37106

Product name: Recombinant human TRIML2 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-155 aa of BC111959

Sequence: MVCGIQEAAENYRKLFQEILNTSREKLEAAKSILTDEQERMAMIQEEEQNFKKMIESEYSMRLRLLNEECEQNLQRQQECISDLNLRETLLNQAIKLATELEEMFQEMLQRLGRVGRENMEKLKESEARASEQVRSLLKLIVELEKKCGEGTLAL

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 tripartite motif family-like 2
别名 EC:2.3.2.27, Probable E3 ubiquitin-protein ligase TRIML2, RING-type E3 ubiquitin transferase TRIML2, SPRY domain-containing protein 6, SPRYD6
计算分子量50 kDa
观测分子量50 kDa
GenBank蛋白编号BC111959
基因名称 TRIML2
Gene ID (NCBI) 205860
RRIDAB_3670164
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity Purification
UNIPROT IDQ8N7C3
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Tripartite motif family like 2 (TRIML2, also known as SPRYD6) is a member of the tripartite motif (TRIM) family of proteins. It probably interacts with p53 to facilitate the modification of p53 with small ubiquitin-like modifier 2 (SUMO2) (PMID: 25256710). By regulating p53, TRIML2 may also be an important factor in the pathogenesis of Alzheimer's disease (PMID: 27471163).

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