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验证数据展示

  • IHC staining of human liver using 13405-1-AP (same clone as 13405-1-PBS)

    IHC staining of human liver using 13405-1-AP (same clone as 13405-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 13405-1-AP (TRIM38 antibody) at dilution of 1:100 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13405-1-PBS in a different storage buffer formulation.

  • WB analysis of human liver using 13405-1-AP (same clone as 13405-1-PBS)

    WB analysis of human liver using 13405-1-AP (same clone as 13405-1-PBS)

    human liver tissue were subjected to SDS PAGE followed by western blot with 13405-1-AP (TRIM38 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13405-1-PBS in a different storage buffer formulation.

  • IF Staining of L02 using 13405-1-AP (same clone as 13405-1-PBS)

    IF Staining of L02 using 13405-1-AP (same clone as 13405-1-PBS)

    Immunofluorescent analysis of (-20℃ Ethanol) fixed L02 cells using 13405-1-AP (TRIM38 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 13405-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

TRIM38 Polyclonal antibody, PBS Only

TRIM38 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 13405-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, IF/ICC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

13405-1-PBS targets TRIM38 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag3840

Product name: Recombinant human TRIM38 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 117-466 aa of BC026930

Sequence: RAPQHKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQIQRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELEEKCQGSAQKLLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKLYFDVKKMLRSHQVSVTLDPDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPCVLGCEGFTSGRRYFEVDVGEGTGWDLGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGYVALTSPPTSLHLHEQPLLVGIFLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPYFQVYQYSPLFLPPPGD

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 tripartite motif-containing 38
别名
计算分子量 465 aa, 53 kDa
观测分子量 53 kDa
GenBank蛋白编号BC026930
基因名称 TRIM38
Gene ID (NCBI) 10475
RRIDAB_2208307
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDO00635
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The proinflammatory cytokines TNFα and IL-1β play central roles in many diseases, including infectious diseases, autoimmunity, and cancers. TRIM38 belongs to the TRIM protein family that is involved in various biological processes, including cell proliferation and apoptosis, innate immunity, and inflammatory response. It has been shown that TRIM38 acts as a suppressor in TOLL-like receptor (TLR)-mediated IFN-β induction by promoting degradation of TRAF6 and NAP1 through the ubiquitinproteasome system. (PMID:24434549)

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